The Prognostic Significance of Left Atrial Appendage Emptying Velocity in Predicting Late Recurrence After Radiofrequency Catheter Ablation in Patients with Nonvalvular Atrial Fibrillation
Objective To investigate the clinical predictive value of left atrial appendage emptying velocity(LAAEV)for late recurrence in patients with nonvalvular atrial fibrillation(NVAF)undergoing radiofrequency catheter ablation(RFC A).Methods Retrospective analysis of the clinical data of 217 patients with NVAF who presented to the Cardiovascular Medicine Department of The First Medical Center of Chinese PLA General Hospital from January 2020 to May 2023 and underwent RFCA for the first time.The recurrence of NVAF after RFCA was followed up by outpatient review,re-hospitalization,and telephone call.According to whether recurred after 3 months,the subjects were divided into a recurrence group(64 cases)and a non-recurrence group(153 cases).The general data of the two groups of patients were counted and compared between the two groups.The factors with statistically significant differences were included in the univariate and multivariate logistic regression models for further analysis to conclude whether LAAEV was an independent risk factor for late recurrence after RFCA in NVAF patients,and the predictive value of LAAEV in late recurrence after RFCA was analyzed according to ROC curve and AUC value.Results The levels of persistent atrial fibrillation,duration of disease,N-terminal pro-brain natriuretic peptide and early recurrence in the recurrent group were higher than those in the non-recurrent group,while LAAEV was lower than that in the non-recurrent group,and the differences were statistically significant(P＜0.05).Logistic regression analysis showed that LAAEV was independently associated with late recurrence after RFCA in patients with NVAF(P＜0.05).The ROC curve shows that the AUC is 0.661,the cutoff is 0.348,the sensitivity is 68.8％,and the specificity is 66.0％.Conclusion LAAEV is an independent risk factor for late recurrence after RFCA in NVAF patients,with significant predictive value.
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