Viral myocarditis(VMC)is a common clinical cardiovascular disease,and inflammatory immune response is the main cause of VMC.Role that neutrophils play in VMC as a part of innate immune response has rarely been studied in the past.However,several studies have indicated that neutrophils can be involved in a variety of diseases through formation of a new defense mechanism called neutrophil extracellular traps(NETs).Moreover,NETs formation has been recently dis-covered in patients with active myocarditis and in myocardial pathological biopsies of VMC model,thus NETs are presumed to play a certain role in pathogenesis of VMC.The present article makes a review on role of NETs in VMC.
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