Objective:To investigate serum levels of 25-(OH)D3,monocyte-to-high density lipoprotein choles-terol ratio(MHR)and neutrophil-to-lymphocyte ratio(NLR)in carotid atherosclerosis(CAS)patients with kid-ney deficiency and blood stasis(KDBS)type,and analyze their relationship with KDBS type CAS.Methods:A total of 247 CAS patients who were treated in our hospltal from Dec 2020 to Dec 2022 were selected and divided into non-kidney deficiency(NKD)group(n=70),kidney-jing deficiency(KJD)group(n=97)and KDBS group(n=80)according to dialectical criteria.The clinical data,serum 25-(OH)D3,MHR,NLR were compared among three groups.Influencing factors for KDBS type CAS were analyzed.Results:Compared with NKD group,there were significant rise in MHR[(0.41±0.27)vs.(0.49±0.20)vs.(0.55±0.20)]in KJD group and KDBS group(P＜0.05 or＜0.01).Compared with NKD group and KJD group,there was significant rise in NLR[(2.55±1.53)vs.(3.14±2.29)vs.(4.03±2.70)]in KDBS group(P＜0.01 all).Compared with NKD group and KJD group,there was significant reduction in serum 25-(OH)D3 level[(24.08±2.87)ng/ml vs.(17.77±1.94)ng/ml vs.(16.24±2.19)ng/ml]in KDBS group(P=0.001 all).Logistic regression analysis showed that serum 25-(OH)D3 was an independent protective factor for KDBS type CAS(OR=0.619,P=0.001),while MHR was its inde-pendent risk factor(OR=6.064,P=0.015).Conclusion:Serum 25-(OH)D3,MHR and NLR are closely associ-ated with kidney deficiency and blood stasis type carotid atherosclerosis,serum 25-(OH)D3 and MHR can be used as auxiliary detection indexes for evaluating carotid atherosclerosis of kidney deficiency and blood stasis type.
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