β-receptor blockers are used to treat cardiovascular disease(CVD),while β-receptor agonists are used to treat chronic obstructive pulmonary disease(COPD).The two drugs have opposite mechanisms of action.Howev-er,there is a close relationship between COPD and CVD,and CVD is related to the severity of pulmonary dysfunc-tion.The use of β-receptor blockers in COPD is still controversial,but studies have shown that cardiac selective β-receptor blockers can reduce mortality in mild and moderate COPD with CVD and reduce the risk of COPD exacerbation,while non-selective β-receptor blockers increase the risk of COPD exacerbation.However,the dosage of cardiac selective β-receptor blockers and its balance with β-receptor agonists in COPD patients with CVD still requires serious treatment.Research on new β-receptor blockers is a problem to be paid close attention to in the future.
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