摘要
睡眠障碍与心血管疾病之间存在密切联系.氧化应激、炎症、交感神经激活、血管内皮功能障碍、自主神经功能障碍及内分泌系统调节异常在睡眠障碍中扮演重要角色,而这些均是心血管疾病及其危险因素的诱因.睡眠障碍与糖尿病、高血压和心血管疾病的发展有关,心血管疾病也会加重睡眠障碍.本文就睡眠障碍和心血管疾病及其危险因素的关系和病理生理机制作一综述.
Abstract
There is a close relationship between sleep disorders and cardiovascular diseases.Oxidative stress,inflam-mation,sympathetic activation,vascular endothelial dysfunction,autonomic nervous dysfunction and abnormal en-docrinological system regulation play critical roles in sleep disorders,all of which are predisposing factors for cardio-vascular diseases and its risk factors.Sleep disorders is related to development of diabetes,hypertension and cardio-vascular diseases,and cardiovascular diseases can also exacerbate sleep disorders.This article makes a review on the relationship among sleep disorders,cardiovascular diseases and its risk factor as well as their pathophysiological mechanisms.
维普
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