首页|阻塞性睡眠呼吸暂停低通气综合征患者发生心血管疾病风险的因素分析

阻塞性睡眠呼吸暂停低通气综合征患者发生心血管疾病风险的因素分析

Analysis of risk factors for cardiovascular diseases in patients with obstructive sleep apnea hypopnea syndrome

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目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者发生心血管疾病(CVD)风险的因素.方法:选择2020年5月至2022年3月淮安市第二人民医院收治的281例OSAHS患者,根据是否并发CVD分为CVD组(63例)和无CVD组(218例).采用课题组设计的OSAHS 一般资料调查问卷对患者开展调查并行单因素分析,将具有临床意义的单因素纳入多因素Logistic回归分析中,分析OSAHS患者发生CVD的影响因素.结果:与无CVD组比较,CVD组年龄明显更大,人体质量指数(BMI)、有CVD家族史、血脂异常比例、空腹血糖(FPG)水平、OSAHS重度比例均显著增加(P<0.05或<0.01).多因素Logistic回归分析结果显示,年龄、BM1、血脂异常、FPG、重度OSAHS是OSAHS患者并发CVD的独立危险因素(OR=2.213~2.482,P<0.05或<0.01).结论:年龄、BMI、血脂异常、FPG、重度OSAHS是OSAHS患者发生CVD的独立危险因素,临床可根据上述因素制定个体化防控对策,对预防CVD的发生具有重要意义.
Objective:To investigate the risk factors of cardiovascular diseases(CVD)in patients with obstructive sleep apnea hypopnea syndrome(OSAHS).Methods:A total of 281 OSAHS patients admitted in Second People's Hospital of Huai'an City between May 2020 and March 2022 were selected and divided into CVD group(n=63)and no CVD group(n=218)according to presence of CVD.The OSAHS general data questionnaire designed by the re-search group was used to investigate the patients and univariate analysis was carried out,and the clinically significant single factors were included in the multivariate Logistic regression analysis.Influencing factors for CVD in OSAHS patients were analyzed.Results:Compared with no CVD group,patients in CVD group had significant higher age,body mass index(BMI),fasting plasma glucose(FPG)level,proportions of CVD family history,dyslipidemia and severe OSAHS(P<0.05 or<0.01).Multivariate Logistic regression analysis indicated that age,BMI,dyslipi-demia,FPG and severe OSAHS were independent risk factors for CVD in OSAHS patients(OR=2.213~2.482,P<0.05 or<0.01).Conclusion:Age,BMI,dyslipidemia,FPG and severe OSAHS are independent risk factors of CVD in OSAHS patients.Individualized prevention and control strategies can be formulated according to above fac-tors in clinic,which is of great significance for prevention of CVD occurrence.

Sleep apnea,obstructiveCardiovascular diseasesRisk factors

孙静、陈莉、怀德、邱月、郭巧玲、李荣芳

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淮安市第二人民医院耳鼻喉头颈外科,江苏淮安 223001

睡眠呼吸暂停,阻塞性 心血管疾病 危险因素

2022年淮安市级自然科学研究计划面上项目江苏省淮安市2023科技创新计划

HAB02213HAP202304

2024

心血管康复医学杂志
福建省康复医学会 中国康复医学会

心血管康复医学杂志

CSTPCD
影响因子:1.157
ISSN:1008-0074
年,卷(期):2024.33(5)