Objective:This study aims to investigate risk factors for bleeding after percutaneous coronary intervention(PCI)and correlation between CRUSADE score and incidence of bleeding.Methods:A total of 130 patients with coronary heart disease(CHD)underwent PCI in Fengfeng General Hospital of North China Medical and Health Group between March 2020 and March 2021 were selected.Bleeding risk after PCI was assessed by CRUSADE scoring system,according to the results,patients were divided into low-medium risk group(n=84,aspirin enteric-coated tablet+clopidogrel therapy)and high risk group(n=46,aspirin enteric-coated tablet+clopidogrel+rabeprazole therapy).General data and bleeding after PCI were compared between two groups;according to presence of bleeding after PCI,patients were divided into bleeding group(n=38)and no bleeding group(n=92).Multivariate Logistic regression was used to analyze influencing factors of bleeding after PCI;Spearman method was used to analyze the correlation between CRUSADE score and incidence of bleeding after PCI.Results:Total incidence of bleeding after PCI in high risk group was significantly higher than that of low-medium risk group(P＜0.001).Compared with patients in no bleeding group,those in bleeding group had significant higher age,heart rate,systolic blood pressure,diastolic blood pressure,proportions of hypertension,diabetes and CRUSEDE high-risk,and significant lower creatinine clearance rate(P＜0.01 all).Multivariate Logistic regression showed that age,hypertension and CRUSADE high-risk were independent risk factors for bleeding after PCI(OR=6.231,8.954,2.453,P＜0.05 or＜0.01),while creatinine clearance rate was its independent protective factor(OR=0.005,P＜0.001).Spearman correlation analysis indicated that CRUSADE score was positively correlated with incidence of bleeding after PCI(r=0.352,P=0.013).Conclusion:Advanced age,hypertensive and CRUSADE high-risk CHD patients after PCI have high risk of bleeding.CRUSADE system assessment can effectively increase predictive efficacy for bleeding after PCI so as to provide early medication and ensure prognosis.
维普
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