摘要
白芍为毛茛科植物芍药的干燥根,主要产于浙江(杭白芍)、安徽(毫白芍)、四川(川白芍),具有平肝止痛、养血调经、敛阴止汗等功效.与白芍来源相近的赤芍为毛茛科植物芍药或川赤芍的干燥根,二者化学成分相似,但由于加工方法、炮制工艺等不同,导致二者功效及临床应用各有偏重,区别明显.现代研究表明,白芍中化学成分丰富,主要包含单萜及其苷类、三萜及其苷类、挥发油类、黄酮类、多酚类等,具有镇痛、抗炎、抗抑郁、保肝、抗肿瘤及抗高血糖等广泛的药理作用.本文从白芍的化学成分出发,对近年有关白芍有效成分及其药理学作用的研究进展进行综述,以期为白芍的综合开发利用提供参考.
Abstract
Paeonia Radix Alba is the dried root of Paeonia lactiflora Pall.in the ranunculus family,which is mainly produced in Zhejiang(Hang Paeony),Anhui(Hao Paeony)and Sichuan(Chuan Paeony).It has the effects of calming liver,relieving pain,nourishing blood,regulating menstrual period,collecting Yin,and preventing perspiration.Similar to Paeonia Radix Alba,Paeonia Radix Rubra is the dried root of Paeonia lactiflora Pall.or Paeonia veitchii Lynch.in the ranunculus family.Although the chemical constituents are similar,the efficacy and clinical application of the two herbal medicines are obviously different owing to their various processing methods and techniques.Modern studies have shown that Paeonia Radix Alba is rich in multiple chemical constituents,mainly including monoterpenoids and their glycosides,triterpenoids and their glycosides,volatile oils,flavonoids,and polyphenols,and has a wide range of pharmacological effects such as analgesia,anti-inflammation,anti-depression,liver protection,anti-tumor,and anti-hyperglycemia.This paper reviews the progress of research on effective constituents of Paeonia Radix Alba and their pharmacological effects to provide references for the comprehensive development and utilization of Paeonia Radix Alba.
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