Extranodal natural killer/T-cell lymphoma(ENKTCL)is a rare malignant tumor associated with EB virus infection,with strong invasiveness.At present,for advanced or relapsed/refractory ENKTCL,it is recommended to use non-an-thracycline drugs containing L-asparaginase in combination with other drugs for chemotherapy,but the long-term survival rate is still low.In recent years,hematopoietic stem cell transplantation,immunotherapy and targeted therapy have received widespread attention,providing new options for the treatment of ENKTCL.This article reviews the therapeutic progress of hematopoietic stem cell transplantation,immunotherapy and targeted therapy in ENKTCL.
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