Objective To explore the influencing factors for visual field defects in patients with advanced glaucoma.Methods Two hundred and six patients(206 eyes)with advanced glaucoma treated in the First Affiliated Hospital of Xinxiang Medical University from January 2019 to January 2023 were selected as the research subjects.The clinical and follow-up data of the patients were retrospectively analyzed.The patients were divided into the temporal visual island group(n=134)and the tubular visual field group(n=72)based on the degree of visual field defects.The risk factors for visual field defects in patients with advanced glaucoma were analyzed through univariate and multivariate logistic regression.Results The univariate logistic regression analysis showed that comorbidity with high myopia,types of glaucoma,peak and mean intraocular pressure during follow-up,types of drugs,and types of cumulative medication use were associated with visual field defects in patients with advanced glaucoma(P<0.05).The multivariate logistic regression analysis showed that comorbidity with high myopia,chronic primary angle closure glaucoma(CPACG),and peak intraocular pressure ≥21 mm Hg(1 mm Hg=0.133 kPa)during follow-up were the independent risk factors for visual field defects in patients with advanced glaucoma(P<0.05).Conclusion The incidence of temporal visual island is high in patients with advanced glaucoma.It is necessary to strengthen intraocular pressure monitoring and related eye health education in patients with high myopia,CPACG,and peak intraocular pressure≥21 mm Hg during follow-up to improve the visual field defects.
glaucomaadvanced stagevisual field defectinfluencing factor