Non-traumatic osteonecrosis of the femoral head(NONFH)is a disabling disease of the hip joint and severe-ly affects the quality of life of patients.The complex pathogenesis of NONFH has not yet been investigated clearly,so clinical diagnosis and treatment are limited.In recent years,multi-omics,as a high-throughput detection and analysis technique,has played an essential role in unraveling the characteristics of NONFH and aiding the diagnosis of the disease.This article reviews the latest applications of and advances in multi-omics including genomics,transcriptomics,proteomics and metabolomics in NONFH,so as to provide new ideas for further exploration of the pathogenesis of NONFH.
关键词
非创伤性股骨头坏死/基因组学/转录组学/蛋白质组学/代谢组学/多组学
Key words
non-traumatic osteonecrosis of femoral head/genomics/transcriptomics/proteomics/metabolomics/multi-omics
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