Objective To investigate the risk factors for postoperative lymph node metastasis in patients with thoracic esophageal squamous cell carcinoma.Methods A total of 105 patients with esophageal squamous cell carcinoma in the thoracic segment who underwent surgical treatment at the Department of Thoracic Surgery of the First Affiliated Hospital of Xinxiang Medical University from January 2020 to June 2022 were selected as the research subjects.The patients were divided into the lymph node metastasis group(n=34)and the non-lymph node metastasis group(n=71)according to whether lymph node metastasis occurred postoperatively.Clinical data of patients were collected.Risk factors for lymph node metastasis in patients with esophageal squamous cell carcinoma in the thoracic segment were analyzed by using univariate and multivariate logistic regression.Results Univariate analysis showed that the pathologic differentiation grade,maximum tumor length,and vascular cancer embolism were associated with lymph node metastasis in patients with esophageal squamous cell carcinoma in the thoracic segment(P<0.05);the patient's age,gender,history of drinking,depth of tumor infiltration,histopathological type,nerve invasion status,and tumor location showed no significant correlation with lymph node metastasis(P>0.05).The multivariate logistic regression analysis revealed that larger maximum tumor length,lower differentiation grade,and the presence of vascular cancer emboli were independent risk factors for lymph node metastasis in patients with esophageal squamous cell carcinoma in the thoracic segment(P<0.05).Conclusion Larger maximum tumor length,lower differentiation grade,and the presence of vascular emboli are risk factors for lymph node metastasis in patients with esophageal squamous cell carcinoma.