首页|2型糖尿病视网膜病变与维生素D的关系研究进展

2型糖尿病视网膜病变与维生素D的关系研究进展

Research progress on the relationship between type 2 diabetic retinopathy and vitamin D

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随着生活方式的改变,肥胖人口在逐渐增多,2型糖尿病(T2DM)患病率也逐年增加,且发病年龄呈逐年下降趋势.糖尿病视网膜病变(DR)是T2DM常见的并发症之一,严重影响患者的生活质量.目前,还没有可以预测和完全阻止DR进展的方法.研究发现,维生素D缺乏患者在补充维生素D后可以有效改善DR,这有望成为预测及治疗DR的新思路和方法.本文将对维生素D在DR发生发展中的作用及其对DR的治疗作用和机制研究进展进行综述,以期为补充维生素D在DR防治中的应用提供依据.
With the change of lifestyle,the obese population is gradually increasing,and the prevalence of type 2 diabetes mellitus(T2DM)is increasing year by year,while the age of onset is declining year by year.Diabetic retinopathy(DR),as one of the common complications of T2DM,has a serious impact on the quality of life of patients.At present,there is no way to predict and completely stop the progression of DR.Studies have shown that vitamin D supplementation can effectively alleviate DR in vitamin D deficiency patients,which is expected to become a new idea and method to predict and treat DR.This article-reviews the role of vitamin D in the occurrence and development of DR,as well as its therapeutic effect and mechanism on DR,in order to provide a basis for the application of vitamin D supplementation in the prevention and treatment of DR.

vitamin Dtype 2 diabetes mellitusdiabetic retinopathy

郭庆、罗云、徐霞、何高芬、吴艳婷

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上海市嘉定区安亭医院内分泌科,上海 201805

维生素D 2型糖尿病 糖尿病视网膜病变

上海市嘉定区卫生健康委员会科研项目

2022-KY-15

2024

新乡医学院学报
新乡医学院

新乡医学院学报

CSTPCD
影响因子:0.999
ISSN:1004-7239
年,卷(期):2024.41(8)
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