Pulmonary hypertension(PH)is a cardiovascular disease characterized by persistent elevation of pulmonary artery pressure and pulmonary vascular resistance,and its pathological basis is remodeling of the pulmonary vasculature.Puerarin,the main active ingredient in Pueraria Mirifica,has been shown to have significant cardioprotective effects,and its mechanism may be to reduce inflammatory response,oxidative stress,and myocardial cell apoptosis.This paper reviews the research progress on the molecular mechanism of puerarin in the treatment of PH,with the aim of providing new strategies and theoretical basis for the clinical treatment of PH.
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