Objective To investigate the distribution characteristics of pathogens in patients with infection after kidney transplantation,and analyze their risk factors.Methods A total of 495 patients who underwent kidney transplantation at the 7th People's Hospital of Zhengzhou from January 2020 to December 2023 were selected as the research subjects,and they were divided into non-infection group and infection group based on whether they were infected within one month after surgery.The infection incidence rate,infection site and distribution of pathogens after kidney transplantation were statistically analyzed,and the risk factors for infection after kidney transplantation were analyzed by using univariate and binary logistic regression.Results The infection incidence rate within one month after kidney transplantation in 495 patients was 16.16％(80/495),of which,the infection mostly occurred in the urinary system,with an incidence rate of 71.43％(65/91).There was no statistically significant difference in the infection incidence rate between living kidney transplantation and cadaveric kidney transplantation(P＞0.05).A total of 109 pathogens were detected in the secretions from the infection sites of 80 patients with infection after kidney transplantation,including 63(57.80％)Gram negative bacteria,43(39.45％)Gram positive bacteria,and 3(2.75％)fungi.The results of univariate analysis showed that preoperative albumin(ALB)and hemoglobin(Hb)levels,preoperative dialysis status,length of hospital stay,and indwelling catheterization time were correlated with postoperative infection(P＜0.05);while the sex,age,hypertension,hyperlipidemia,diabetes,coronary heart disease,dialysis time,preoperative white blood cell count,neutrophil count and serum creatinine level,donor status,and rejection after transplantation were not associated with postoperative infection(P＞0.05).The results of binary logistic regression analysis showed that preoperative low levels of ALB and Hb,preoperative dialysis,length of hospital stay＞30 days,and indwelling catheterization time＞3 days were risk factors for infection after kidney transplantation(P＜0.05).Conclusion The risk of bacterial infection after kidney transplantation is high,and the urinary system is one of the common sites of infection.The preoperative low levels of ALB and Hb,preoperative dialysis,length of hospital stay＞30 days,and indwelling catheterization time＞3 days are risk factors for infection after kidney transplantation.
kidney transplantationinfectiondistribution of pathogensrisk factors
维普
万方数据
