The regulation of autophagy by traditional Chinese medicine(TCM)has a good therapeutic effect on osteoar-thritis(OA).It mainly involves several mechanisms,such as inhibiting the production of inflammatory factors,regulating chon-drocyte proliferation and apoptosis,resisting cellular oxidative stress,maintaining chondrocyte homeostasis and restoring the extracellular matrix.In this article,the mechanisms of TCM in treating OA by regulating autophagy are reviewed,providing new ideas for the study of TCM in the prevention and treatment of OA.
osteoarthritisautophagytraditional Chinese medicine