Objective To analyze the occurrence,peak bilirubin,and etiology of neonatal hyperbilirubinemia in our hospital in the past two years,to provide data for the study of high-altitude neonatal bilirubin,and to provide a basis for the prevention and standardized management of neonatal bilirubinemia.Methods The study retrospectively sum-marized the Tibetan near-term Tibetan infants(>35 weeks of gestation)who presented to the Department of Pediatrics of the People's Hospital of Xizang Autonomous Region from January 2019 to July 2021 with jaundice-related com-plaints,and described the distribution of bilirubin peaks,comparisons between different gestational ages,analysis of comorbidities,and characterization of children with encephalopathy.Results Among the 299 cases of neonatal hyper-bilirubinemia,109 cases(35.8%)were severe hyperbilirubinemia and 6 cases of acute bilirubinous encephalopathy,accounting for 5.7%of severe hyperbilirubinemia.The age of jaundice was 4 days(range:1～26 days),the average age of admission was 7 days(range:1～30 days),and the peak TSB was 342.45±65.23 μmol/L.Ninety-one percent of the included cases had varying degrees of infection,and two had ABO autoimmune hemolysis.Conclusion The data of this study showed the peak distribution of bilirubin in Tibetan near-term neonates,and the proportion of infants with severe hyperbilirubinemia and encephalopathy was relatively high,suggesting that the audience of neonatal jaundice related scientific knowledge should be expanded,and a systematic and comprehensive follow-up should be established to provide a basis for the prevention and standardized management of severe hyperbilirubinemia.
维普
万方数据
