A retrospective study on Helicobacter pylori infection and serum gastric function levels in common Tibetan patients with gastric diseases in Lhasa
Objective To study the infection of Helicobacter pylori and the serum gastric function level of patients with gastric diseases in Tibetan population.Methods A retrospective analysis was performed for 211 Tibetan patients who participated in physical examination at the Physical Examination Center of Fukang Hospital in Tibet from Octo-ber 2022 to October 2023.13C and 14C urea breath tests were performed to detect the infection of Helicobacter pylori(Hp),enzyme-linked immunosorbent assay was used to detect the serum gastric function level of the patients,and gas-troscopy was used to observe the gastric mucosa of the patients.The differences in Hp infection and serum gastric function indexes in patients with different gastric diseases were compared.Results The patients were divided into CAG group and CNG group according to their mucosal condition under gastroscopy.The levels of PGI and PGR in the CAG group were lower than those in the CNG group,while the levels of G-17 were higher than those in the CNG group.The levels of PGⅡ and G-17 in the Hp infection group were higher than those in the negative group,while the PGR level was lower than that in the negative group,and the differences were statistically significant(P<0.05).Based on the ROC curve,the optimal cut-off value for the diagnosis of CAG was obtained.Conclusion Serum levels of PGI,PGR,and G-17 can be used as serological indicators for CAG and CNG screening in the Tibetan population in Lhasa.There is a significant correlation between serum gastric function indexes and gastric mucosal atrophy in the lo-cal population.Targeted interventions are needed to reduce the risk of gastric diseases and protect the health of the health of people in the region.
NETL
NSTL
万方数据
维普
