Objective To explore the clinical efficacy of Tibetan medicine Sanwei Ganlu Wan,Xisi San and Zhudi Wan in the treatment of reflux esophagitis.Methods A total of 192 patients with reflux esophagitis admitted from March 2020 to March 2022 were divided into control group and observation group by using a random number table method.The control group was treated with conventional Western medicine,and the observation group was treated with Tibetan medicine for a course of treatment for 20 days.The overall efficacy,symptom score,esophageal muco-sal grading,adverse reactions were compared,and a 6-month follow-up was carried out to investigate the recurrence of reflux esophagitis.Results The total effective rate of treatment in the observation group was 96.88％,higher than that in the control group(89.58％,P<0.05).After one course of treatment,belching reflux,heartburn,retrosternal pain and discomfort,and endoscopic esophageal mucosal grading scores in both groups were significantly lower than those before treatment,and the corresponding scores of 1.14±0.71,0.51±0.50,0.74±0.44 and 0.96±0.48 in the ob-servation group were lower than those in the control group(1.33±0.64,0.84±0.37,1.02±0.41,and 1.10±0.51)(P<0.05).The incidence of adverse reactions was 1.04％in observation group and 2.08％in the control group,with no difference(P>0.05).The recurrence rate of the disease was 6.25％in observation group and 16.67％in the control group(P<0.05).Conclusion The commonly used Tibetan medicine have good clinical efficacy in the treatment of reflux esophagitis,which can improve the local congestion and related symptoms and signs,reduce disease recur-rence,and have good safety.
Tibetan MedicineReflux esophagitisMaxiu SuonaiSanwei Ganlu WanXisi SanZhudi Wan
NETL
NSTL
万方数据
