Study on the effect of high-flux dialysis on renal anemia in patients on maintenance hemo-dialysis at high altitudes
Objective To explore the effect of high-flux dialysis on renal anemia in patients with maintenance hemo-dialysis at high altitudes.Methods A total of 100 patients who underwent clinical treatment for maintenance hemodi-alysis at the Blood Purification Center of the People's Hospital of the Tibet Autonomous Region from January 2021 to February 2022 were selected.The patients were randomly divided into observation group(50 cases)and control group(50 cases).The observation group was given high-flux hemodialysis,and the control group was given low-flux hemodialysis,and the regular dialysis was followed up 12 months.Changes of hemoglobin,serum creatinine,urea ni-trogen and C-reactive protein levels before and after treatment were compared between the two groups;the changes in erythropoietin dose and SF-36 scale score were compared between the two groups;and the urea clearance index Kt/V and the incidence of adverse reactions were compared between the two groups.Results A total of 91 cases were successfully followed up.After 12 months of dialysis treatment,the hemoglobin level and Kt/V of the observation group were higher than those of the control group,and the weekly dose of erythropoietin was lower than that of the control group.The differences were statistically significant(P＜0.05 for both).After treatment,the average score of SF-36 scale in the observation group(61.72±8.07)was higher than that in the control group(49.98±7.85)(P＜0.05),and the quality of life in the observation group was higher than that in the control group.At the same time,there was no statistically significant difference in the total incidence of adverse reactions between the two groups(P＞0.05).Conclusion High-flux dialysis can improve renal anemia and quality of life in maintenance hemodialysis patients,and has fewer adverse reactions and high safety.
High altitudeMaintenance hemodialysisAnemiaHigh flux dialysis
万方数据
维普
