Clinical analysis of esophageal variceal bleeding in Tibetan patients with cirrhosis
Objective To investigate the risk factors of esophageal variceal bleeding(EVB)in Tibetan patients with cirrhosis.Methods A total of 119 patients with cirrhosis and esophageal varices(EV)who were hospitalized in the Department of Gastroenterology of the People's Hospital of Xizang Autonomous Region from January 2021 to April 2022 were selected and divided into bleeding group and non-bleeding group.The clinical data of the patients were analyzed.The influencing factors of cirrhosis complicated with EVB were explored by multivariate Logistic regres-sion analysis.Results Among the 119 patients,the male to female ratio was 3.6:1,with 77 cases(64.7％)in the bleeding group and 42 cases(35.3％)in the non-bleeding group.Among them,there were 28 cases(23.5％)of alco-holic cirrhosis,78 cases(65.5％)of hepatitis B cirrhosis,and 13 cases(11.0％)of other causes of cirrhosis.The re-sults of multivariate Logistic regression analysis showed that age(OR=1.058,95％CI=1.001～1.118),history of bleed-ing(OR=7.524,95％CI=1.189～47.598),Child-Pugh grade(OR=6.211,95％CI=1.852～20.836),Hb(OR=15.034,95％CI=3.407～66.347),activated partial prothrombin time(APTT)(OR=0.148,95％CI=0.029～0.767),Aspartate ami-notransferase(AST)(OR=0.168,95％CI=0.033～0.860)and degree of EV(OR=4.792,95％CI=1.331～17.249)were the independent factors for EVB in cirrhosis.Conclusion Age,previous bleeding history,Child-Pugh grade,Hb and EV severity were independent risk factors for EVB in patients with cirrhosis in Xizang,while APTT and AST were pro-tective factors.
万方数据
维普
