首页|桃红四物汤联合拇指背侧筋膜皮瓣修复对指端软组织缺损皮瓣存活率的影响

桃红四物汤联合拇指背侧筋膜皮瓣修复对指端软组织缺损皮瓣存活率的影响

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目的:观察桃红四物汤联合拇指背侧筋膜皮瓣修复对指端软组织缺损患者皮瓣存活率的影响。方法:选取2022年12月—2023年4月于海宁市第二人民医院进行治疗的80例指端软组织缺损患者为研究对象,按照随机数字表法分为对照组和治疗组各40例。对照组术后给予常规治疗,治疗组在对照组基础上联合桃红四物汤治疗,2组均治疗7 d。比较2组临床疗效、皮瓣存活率及凝血功能。结果:治疗组总有效率为95。00%(38/40),高于对照组77。50%(31/40)(P<0。05)。治疗组皮瓣存活率为95。00%(38/40),高于对照组77。50%(31/40)(P<0。05)。术后第7天,2组活化部分凝血活酶时间(APTT)、凝血酶原时间(PT)长于术前,纤维蛋白原(Fib)水平低于术前(P<0。05);治疗组PT、APTT长于对照组,Fib水平低于对照组(P<0。05)。结论:桃红四物汤联合拇指背侧筋膜皮瓣修复对指端软组织缺损患者具有较好的疗效,能够提高皮瓣存活率,改善凝血功能。
Effect of Taohong Siwu Decoction Combined with Fascial Flap Repair of Dorsal Thumb on Flap Survival Rate of Fingertip Soft Tissue Defect
Objective:To observe the effect of the therapy of Taohong Siwu Decoction combined with fascial flap repair of dorsal thumb on flap survival rate of patients with fingertip soft tissue defect.Methods:A total of 80 patients with fingertip soft tissue defects treated at the Second People's Hospital of Haining from December 2022 to April 2023 were selected as the study subjects and randomly divided into the control group and the treatment group,with 40 patients in each group.The control group was given conventional treatment after surgery,and the treatment group was additionally treated with Taohong Siwu Decoction on the basis of the treatment of the control group.Both groups were treated for seven days.The clinical effects,flap survival rates and coagulation function were compared between the two groups.Results:The total effective rate was 95.00%(38/40)in the treatment group,higher than that of 77.50%(31/40)in the control group(P<0.05).The flap survival rate was 95.00%(38/40)in the treatment group,higher than that of 77.50%(31/40)in the control group(P<0.05).On the seventh day after surgery,the activated partial thromboplastin time(APTT)and prothrombin time(PT)in the two groups were longer than those before surgery,and the fibrinogen(Fib)levels were lower than those before surgery(P<0.05);the PT and APTT in the treatment group were longer than those in the control group,and the Fib level was lower than that in the control group(P<0.05).Conclusion:The therapy of Taohong Siwu Decoction combined with fascial flap repair of dorsal thumb has a great curative effect on patients with fingertip soft tissue defect,which can increase the flap survival rate and improve the coagulation function.

Fingertip soft tissue defectTaohong Siwu DecoctionFascial flap repair of dorsal thumbFlap survival rateCoagulation function

吴永祥、周文君、张忠仁、屈曹斌、崔岩

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海宁市第二人民医院骨科,浙江 海宁 314419

中国人民武装警察部队海警总队医院手足外科,浙江 嘉兴 314400

指端软组织缺损 桃红四物汤 拇指背侧筋膜皮瓣修复 皮瓣存活率 凝血功能

2025

新中医
广州中医药大学 中华中医药学会

新中医

影响因子:0.595
ISSN:0256-7415
年,卷(期):2025.57(1)