Objective To analyze the related causes of high grade squamous intraepithelial lesion(HSIL)with positive margin af-ter cervical conization.Methods From January 2016 to December 2020,776 patients with cervical HSIL and conectomy were retro-spectively analyzed.The correlation of treatment,age,glands involved,HPV infection,multipoint lesions and positive incisal mar-gin were analyzed.Results Of 776 patients,143(18.32％)had positive margins after cone resection.Univariate analysis showed that positive incisal margin after HSIL conectomy was associated with LEEP surgery(P＜0.05),involved glands(P＜0.01)and multi-point lesions(P＜0.05),but not HPV infection(P＞0.05)or age(P＞0.05).Multivariate regression analysis showed that LEEP sur-gery,glandular involvement and multiple cervical lesions were independent risk factors for positive incisal margin after HSIL conec-tomy(P＜0.05).Conclusion LEEP surgery,glandular involvement and cervical multipoint lesions are high risk factors for positive margin after HSIL conectomy.Attention should be paid to the treatment.
万方数据
维普
