静息全周期比值与冠脉血流储备分数的一致性
Study on consistency of resting full-cycle ratio and fractional flow reserve
王佳旺 1吴琼 1刘莲莲 1韩雪 1董传政 1于靖1
作者信息
- 1. 沧州市中心医院心内科,河北沧州 061001
- 折叠
摘要
目的 评价静息全周期比值(resting full-cycle ratio,RFR)与金标准冠脉血管储备分数(fractional flow reserve,FFR)的一致性.方法 纳入 2021年 9月～2022年 9月在沧州市中心医院接受侵入性生理学检查的冠心病患者.以RFR≤0.89作为参考值与FFR≤0.80作为参考值进行比较,评价RFR与FFR一致性,RFR的敏感性、特异性、阳性预测值、阴性预测值等指标.结果 本研究共纳入 138例患者,共 189支血管.以RFR≤0.89作为参考值与 FFR≤0.80作为参考值比较,两种方法一致性达 81.5%,并具有统计学意义(R2=0.629,P<0.01),RFR≤0.89作为参考值其敏感度 70.1%,特异度 87.7%,阳性预测值 75.8%,阴性预测值 84.3%,准确率81.5%,ROC曲线下 AUC面积为 0.889(95%CI:0.842～0.937,P<0.01),RFR的 cutoff值:0.915.约登指数为0.609.结论 RFR与金标准FFR具有良好的相关性,是冠脉生理学评估方法的选择之一.
Abstract
AIM To evaluate the agreement between resting full-cycle ratio(RFR)and fractional flow reserve(FFR)with the currently recommended thresholds.METHODS The study included coronary heart disease patients undergoing invasive physiology check from September 2021 to September 2022 in our hospital.Comparison between RFR≤0.89 and FFR≤0.80 value was made to evaluate the sensitivity,specificity,positive predictive value and negative predictive value of RFR.RESULTS A total of 189 lesions were evaluated in 138 patients.Significant correlation was observed(R2=0.629,P<0.01)between the two techniques,with 81.5%agreement between RFR≤0.89 and FFR≤0.80(sensitivity 70.1%,specificity 87.7%,positive predictive value 75.8%,negative predictive value 84.3%,and accuracy 81.5%).The AUC area under the ROC curve was 0.889(95%CI:0.842～0.937,P<0.01).The Youden index was 0.609.CONCLUSION Significant agreement is found between RFR and FFR with the recommended thresholds and they can be used for coronary physiology assessment.
关键词
静息全周期比值/冠脉血管储备分数/冠状动脉介入治疗/冠心病Key words
RFR/FFR/percutaneous coronary intervention/coronary heart disease引用本文复制引用
出版年
2024
NETL
NSTL
万方数据