重庆市艾滋病病例抗病毒治疗效果评价
Effect Evaluation of Highly Active Antiviral Therapyfor AIDS in Chongqing Municipality
何惊春 1李南 1王志勇 1周全华 2张臻 3陈敏 4凌华 2张敏 2吴国辉2
作者信息
- 1. 九龙坡区疾病预防控制中心 重庆400039
- 2. 重庆市疾病预防控制中心
- 3. 渝中区疾病预防控制中心
- 4. 沙坪坝区疾病预防控制中心
- 折叠
摘要
目的 对重庆市140例艾滋病患者抗病毒治疗进行分析,为深入规范开展抗病毒治疗工作提供依据.方法 选择2011-01/12开始抗病毒治疗的140例患者为对象,对其治疗过程中的CD4+T淋巴细胞绝对计数和病毒载量值的变化情况进行分析.结果 治疗前,病例的CD4+T淋巴细胞计数均值为(273±99)个/μl,治疗12个月,治疗病例CD4+T淋巴细胞计数呈明显上升趋势,均值为(447±288)个/μl,117例进行了病毒载量检测,其中70.9％的病例病毒载量计数下降到检测限以下.结论 重庆市艾滋病例在接受抗病毒治疗1年后,治疗效果明显,病例状态持续稳定.
Abstract
Objective To evaluate the curative effect of antiviral therapy for AIDS in Chongqing and provide a basis for promoting Highly active antiretroviral therapy (HARRT) work.Methods During Jan.to Dec.in 2011, 140 patients receiving HARRT were recruited, the CD4 + T lymphocyte of them as well as viral load were detected regularly during the course of the treatment.Results Before the treatment, the mean CD4+Tlymphocyte count was 273 ±-99/ul.After 12 months of treatment, the mean CD4+ Tlymphocyte count reached to 447 -± 288/ul.Of the 140 cases, 117 received viral load test and 70.9％ of their result decreased to the detection limit.Conclusion After one year treatment, the therapeutic effect of HARRT on AIDS is obvious in Chongqing, and the status of the cases remains stable.
关键词
艾滋病/CD4+淋巴细胞/抗反转录病毒治疗Key words
AIDS/CD4 + T lymphocyte/antiviral therapy引用本文复制引用
基金项目
中国全球基金艾滋病项目(CHN-304-G03-H)
出版年
2015
NETL
NSTL
维普
万方数据