Investigation and disposal of a suspected outbreak of carbapenem-resistant Klebsiella pneumoniae nosocomial infection in intensive care unit
Objective To investigate and analyze an outbreak of suspected carbapenem-resistant Klebsiella pneumoniae(CRKP)infection in the intensive care unit(ICU)of a hospital,and to provide evidence for the prevention and control of nosocomial infection outbreak caused by multi-drug resistant bacteria.Methods From December 30,2019 to January 14,2020,an on-site epidemiological investigation was conducted on the 7 CRKP patients detected by the ICU of the hospital in Luzhou City.SAS 9.4 was used to statistically analyze the results,and P<0.05 was considered to be statistically significant.Results Among the 7 CRKP patients in this ward,4 were judged to be nosocomial infection cases.A total of 80 specimens were collected,such as surfaces of high-frequency contact objects in the department of 7 patients with CRKP,hand surfaces of patients in the hospital,hand surfaces of ward staff,bed handrails,bed edges,bedside tables,ventilator panel and inner diameter of catheter,outer edge of tracheal catheter mouth,button of electrocardiogram monitor and computer keyboard of working areas.Among them,65 surface specimens of environmental objects,15 hand surface specimens and 1 hand surface specimen of a patient(bed 7 in ICU)were detected with CRKP,with a detection rate of 1.25%.And no CRKP was detected in the other specimens.After measures such as isolation and ward cleaning and disinfection were conducted,there was no new CRKP nosocomial infection case in nearly 2 months of follow-up and monitoring.Conclusions This outbreak of suspected CRKP nosocomial infection was caused by the pathogen contamination of the environment without centralized isolation measures for CRKP infected patients.
intensive care unitcarbapenem-resistant Klebsiella pneumoniae(CRKP)nosocomial infectionoutbreak