Analysis of surey reswas on enterovirus carrying status among 233 healthy preschool children in 2 cities/counties of Aba Prefecture in 2023
Objective To survey the enterovirus(EV)carrying status and type distribution among healthy children in Maerkang City and Hongyuan County of Aba Tibetan and Qiang Autonomous Prefecture,and to provide basis for formulating enterovirus prevention and control strategy.Methods From March 29,2023 to April 23,2023,stool samples were collected from healthy preschool children in one kindergarten in Maerkang City and Hongyuan County of Aba Tibetan and Qiang Autonomous Prefecture,respectively,for EV nucleic acid detection and nucleotide sequence analysis to analyze EV type distribution.The results of EV detection were analyzed by SPSS 19.0 software.Group comparisons were conducted by x2 test.The test level was α=0.05(bilateral).Results A total of 233 healthy children were tested,and 52 samples were positive for EV nucleic acid.The positive detection rate was 25.2％(31/123)in Maerkang City and 19.1％(21/110)in Hongyuan County,respectively.The positive detection rate of EV was 24.6％(28/114)in males and 21.2％(24/113)in females,and there was no significant difference in the EV positive detection rate between males and females(x2=0.355,P=0.551).The EV positive detection rate was 30.7％(23/75)in the 3-year age group,27.6％(21/76)in the 4-year age group,and 9.8％(8/82)in the 5-year age group.There were significant differences in EV detection rate among all age groups(x2=11.717,P=0.003).A total of 10 types of EV were identified from the 52 samples that tested positive for EV nucleic acid,among which,Maerkang City had 9 types and Hongyuan County had 7 types.Among these 10 types,CV B2 accounted for 38.5％(20/52),E6 and CV A6 accounted for17.3％(9/52),respectively,CV A4 accounted for 11.5％(6/52),CV A2 and CV A5 accounted for 3.8％(2/52),and CV A13,CV A19,E29 and E9 accounted for 1.9％(1/52),respectively.Conclusions The latent infection rate of EV in preschool children,especially healthy children under 5 years old in Maerkang City and Hongyuan County in Aba Tibetan and Qiang Autonomous Prefecture was high,and CVB2 was the main prevalent strain.CVB2 and E6 were detected in multiple specimens from one kindergarten,suggesting local close contact transmission.Health education and prevention and control measures should be strengthened for preschool children to reduce the chance of infection and reduce the infection rate of enterovirus.
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