60岁及以上老年住院患者中肌少症患病情况及其危险因素的Meta分析
Meta-analysis prevalence and risk factors of sarcopenia in hospitalized elderly patients aged 60 years and above
王昆 1曾翔 1王兆兰 2郭雅乐 2李军文3
作者信息
- 1. 成都医学院护理学院,成都 610500
- 2. 成都中医药大学护理学院,成都 610075
- 3. 成都市第一人民医院护理部,成都 610095
- 折叠
摘要
目的 通过Meta分析的方法来探讨≥60岁的老年住院患者肌少症的患病情况和危险因素,为老年住院患者肌少症的早期管理提供循证依据.方法 检索维普、知网、万方、PubMed、Embase、Web of Science和the Cochrane Library中关于老年住院患者肌少症患病情况和危险因素的文献,检索时限为建库至2023年4月,采用Review Manager 5.4和Stata 16.0软件进行Meta分析.结果 最终纳入13篇文献,样本量累计4626例,其中肌少症患者1410例.Meta分析结果显示,老年住院患者肌少症的总体患病率为31％(95％CI:25％～38％),男性患病率为32％(95％CI:28％～37％),女性为40％(95％CI:34％～45％).危险因素的Meta分析结果显示,高年龄(OR=1.43,95％CI:1.27～1.61)、性别(女性)(OR=1.77,95％CI:1.48～2.11)、骨质疏松(OR=3.4,95％CI:1.85～8.72)、体育锻炼不足(OR=1.83,95％CI:1.54～2.19)、营养不良(OR=1.6,95％CI:1.43～1.79)是老年住院患者发生肌少症的危险因素.结论 老年住院患者肌少症的患病率较高,且女性高于男性,年龄、性别、骨质疏松、体育锻炼不足、营养状况是老年住院患者发生肌少症的危险因素,应积极进行早期的干预,以减少肌少症的发生,提高老年住院患者的生存质量.
Abstract
Objective To explore the prevalence and risk factors of sarcopenia in hospitalized elderly patients over 60 years old by a meta-analysis,and to provide evidence-based reference for the early management of sarcopenia in hospitalized elderly patients.Methods The literature on the prevalence and risk factors of sarcopenia in elderly inpatients in VIP,CNKI,Wanfang,PubMed,Embase,Web of Science and the Cochrane Library from the establishment of the databases to April 2023 was searched.And Review Manager 5.4 and Stata 16 were used for the meta-analysis.Results A total of 13 articles were included finally,with a total sample size of 4 626 cases,including 1410 patients with sarcopenia.The results of meta-analysis showed that the overall prevalence of sarcopenia in elderly inpatients was 31％(95％confidence interval(CI):25％-38％),32％(95％CI:28％-37％)in men,and 40％(95％CI:34％-45％)in women.The meta-analysis of risk factors showed that age(odds ratio OR=1.43,95％CI:1.27-1.61),sex(OR=1.77,95％CI:1.48-2.11),osteoporosis(OR=3.4,95％CI:1.85-8.72),physical activity(OR=1.83,95％CI:1.54-2.19)and nutritional status(OR=1.6,95％CI:1.43-1.79)were risk factors of sarcopenia in elderly inpatients.Conclusions The prevalence of sarcopenia in hospitalized elderly patients was relatively high,and the prevalence of women was higher than that of men.Age,gender,osteoporosis,physical exercise and nutritional status were the risk factors for the occurrence of sarcopenia in hospitalized elderly patients.Thus,early intervention should be actively carried out to reduce the occurrence of sarcopenia and improve the quality of life of hospitalized elderly patients.
关键词
肌少症/老年/住院患者/患病率/危险因素Key words
sarcopenia/elderly/inpatients/prevalence/risk factors引用本文复制引用
出版年
2024
NETL
NSTL
万方数据