Meta-analysis on the incidence of nosocomial infection in Stroke Patients in China
Objiective To evaluate the occurrence systematically of nosocomial infection in stroke patients,and to provide a basis for the management and control of nosocomial infection.Methods The English and Chinese literature from Pubmed,Web of Science,embase,Cochrane Library,CNKI,VIP,Wanfang Data,and CBM databases up to June 2023 were searched by using computer systems,the eligible literature was analyzed by using Statal 4.0,and the random effect model or fixed effect model was determined according to the size of I2.Results A total of 34 publications were included,which including 36 066 participating stroke patients.The results of the Meta-analysis showed that the incidence of hospital-acquired infection in stroke in China was 13.8%(95%CI:12.1%-15.5%).The results of subgroup analysis showed that the incidence of hospital infection was 14.2%(95%CI:12.1%-16.5%)and 13.7%(95%CI:11.5%-16.0%)in men and women,respectively.The incidence rates of age ≥60 years and<60 years were 15.8%(95%CI:12.6%-19.3%)and 8.1%(95%CI:6.4%-10.0%).The incidence of different sites were 1.7%(95%CI:1.0%-2.5%)in the upper respiratory tract,3.9%(95%CI:2.6%~5.5%)in the lower respiratory tract,3.0%(95%CI:2.1%-4.0%)in the urinary tract,and 1.1%(95%CI:0.6%-1.7%)in the gastrointestinal tract.The incidence of hospital stay ≥30 days was 20.5%(95%CI:3.3%-46.8%)and<30 days was 14.2%(95%CI:8.4%-21.1%).Incidence of different stroke types:cerebral hemorrhage was 19.5%(95%CI:13.9%-25.8%)and cerebral infarction was 12.4%(95%CI:9.6%-15.5%).Conclusions The overall incidence of hospital-acquired infections in stroke patients in China is high,with a higher incidence in women than in men,and the incidence of infection will be higher in patients older than 60 years old,hospitalized for more than 30 days,and with cerebral hemorrhage,infection sites mainly in the lower respiratory and urinary tracts,so prevention and infection control should be strengthened in clinical work.