首页|中国脑卒中患者医院感染发生率的Meta分析

中国脑卒中患者医院感染发生率的Meta分析

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目的 系统评价脑卒中患者医院感染的发生率情况,为医院感染的管控提供依据.方法 检索Pubmed、Web of Science、embase、Cochrane图书馆、CNKI、VIP、Wanfang Data、CBM数据库建库至2023年6月的中英文文献,将符合条件的文献使用Stata14.0进行Meta分析,若I2>50%则使用随机效应模型,反之选择固定效应模型.结果 总共纳入34篇文献,包括了 36066例参与调查的脑卒中患者.Meta分析结果显示,中国脑卒中医院感染的发生率为13.8%(95%CI:12.1%~15.5%).亚组分析的结果显示,男、女性医院感染的发生率分别为14.2%(95%CI:12.1%~16.5%)、13.7%(95%CI:11.5%~16.0%);年龄≥60岁、<60岁的发生率为 15.8%(95%CI:12.6%~19.3%)、8.1%(95%CI:6.4%~10.0%);不同部位的发生率为:上呼吸道 1.7%(95%CI:1.0%~2.5%)、下呼吸道 3.9%(95%CI:2.6%~5.5%)、泌尿道 3.0%(95%CI:2.1%~4.0%)、消化道 1.1%(95%CI:0.6%~1.7%);住院时间≥30d的发生率为20.5%(95%CI:3.3%~46.8%)、<30d为 14.2%(95%CI:8.4%~21.1%);不同卒中类型的发生率:脑出血为 19.5%(95%CI:13.9%~25.8%)、脑梗死为 12.4%(95%CI:9.6%~15.5%).结论 中国脑卒中患者医院感染的总体发生率较高,其中女性高于男性,年龄大于60岁、住院时间超过30d、脑出血的患者感染发生率会更高,感染部位以下呼吸道和泌尿道为主,因此在临床工作中要更有针对性的进行预防,控制感染.
Meta-analysis on the incidence of nosocomial infection in Stroke Patients in China
Objiective To evaluate the occurrence systematically of nosocomial infection in stroke patients,and to provide a basis for the management and control of nosocomial infection.Methods The English and Chinese literature from Pubmed,Web of Science,embase,Cochrane Library,CNKI,VIP,Wanfang Data,and CBM databases up to June 2023 were searched by using computer systems,the eligible literature was analyzed by using Statal 4.0,and the random effect model or fixed effect model was determined according to the size of I2.Results A total of 34 publications were included,which including 36 066 participating stroke patients.The results of the Meta-analysis showed that the incidence of hospital-acquired infection in stroke in China was 13.8%(95%CI:12.1%-15.5%).The results of subgroup analysis showed that the incidence of hospital infection was 14.2%(95%CI:12.1%-16.5%)and 13.7%(95%CI:11.5%-16.0%)in men and women,respectively.The incidence rates of age ≥60 years and<60 years were 15.8%(95%CI:12.6%-19.3%)and 8.1%(95%CI:6.4%-10.0%).The incidence of different sites were 1.7%(95%CI:1.0%-2.5%)in the upper respiratory tract,3.9%(95%CI:2.6%~5.5%)in the lower respiratory tract,3.0%(95%CI:2.1%-4.0%)in the urinary tract,and 1.1%(95%CI:0.6%-1.7%)in the gastrointestinal tract.The incidence of hospital stay ≥30 days was 20.5%(95%CI:3.3%-46.8%)and<30 days was 14.2%(95%CI:8.4%-21.1%).Incidence of different stroke types:cerebral hemorrhage was 19.5%(95%CI:13.9%-25.8%)and cerebral infarction was 12.4%(95%CI:9.6%-15.5%).Conclusions The overall incidence of hospital-acquired infections in stroke patients in China is high,with a higher incidence in women than in men,and the incidence of infection will be higher in patients older than 60 years old,hospitalized for more than 30 days,and with cerebral hemorrhage,infection sites mainly in the lower respiratory and urinary tracts,so prevention and infection control should be strengthened in clinical work.

strokecross infectionincidenceMeta-analysis

郭雅乐、李军文、王兆兰、曾翔、王昆

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成都中医药大学,成都 610075

成都市第一人民医院/成都市中西医结合医院,成都 610095

成都医学院,成都 610500

脑卒中 医院感染 发生率 Meta分析

四川省科普培训项目

2022JDKP0019

2024

预防医学情报杂志
中华预防医学会,四川省疾病预防控制中心

预防医学情报杂志

CSTPCD
影响因子:0.681
ISSN:1006-4028
年,卷(期):2024.40(9)
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