重庆市渝北区372例既往丙型肝炎病例知晓和抗病毒治疗情况调查及影响因素分析
Investigation and analysis on influencing factors about awareness and antiviral treatment status of 372 previous cases of hepatitis C in Yubei District of Chongqing
刘惠 1马雪梅 1叶茂 1金懿1
作者信息
- 1. 重庆市渝北区疾病预防控制中心,重庆 401120
- 折叠
摘要
目的 了解重庆市渝北区既往报告丙型病毒性肝炎患者当前感染状态、抗病毒治疗情况及影响因素,为消除丙肝危害提供参考依据.方法 选择中国疾病预防控制信息系统中2004-2021年既往报告现住址为重庆市渝北区的丙肝病例,于2023年进行现场问卷调查,采集血液检测病毒载量及基因分型,使用SPSS 21.0软件进行整理分析,采用卡方检验、线性回归模型和Logistic多因素回归分析影响丙肝知识知晓情况和抗病毒治疗的相关因素,检验水准α=0.05.结果 共调查丙肝既往病例372例,该人群丙肝防治知识平均知晓率为52.11％(2 326/4 464),抗病毒治疗率为52.96％(197/372).核酸阳性病例占30.91％(115/372).共发现5种基因型,以3型为主,占47.83％,其中3b型占28.70％(33/115),3a型占19.13％(22/115).多元线性回归模型分析显示,文化程度越高、调查前知道感染情况和有治疗过的患者知晓率更高;Logistic多因素回归分析显示,有职业、高中及以上文化程度的患者抗病毒治疗概率较高.结论 2004-2021年渝北区既往报告丙肝患者的防治知识知晓率及接受抗病毒治疗率较低,需加强对针对性宣传教育,提高患者健康意识.
Abstract
Objective To understand the current infection status of viral hepatitis C patients in Yubei District,the status of anti-viral therapy and its influencing factors,so as to provide reference for eliminating the harm of hepatitis C.Methods Hepatitis C cases with past reports from 2004 to 2021 in the Chinese Disease Prevention and Control Information System were selected,currently residing in Yubei District of Chongqing.An on-site questionnaire survey were conducted in 2023,blood samples were collected for virus load and genotype testing,SPSS 21.0 was used for analysis.Chi-square test and linear regression model was used to analyze the factors affecting knowledge of hepatitis C and antiviral treatment,with a test level of α=0.05.Results Among 372 cases of hepatitis C,the average awareness rate of HCV prevention and treatment knowledge was 52.11％(2 326/4 464),and the rate of anti-virus treatment was 52.96％(197/372).30.91％(115/372)of the cases were positive for nucleic acid.A total of five genotypes were found.Type 3 was the dominant genotype,accounted for 47.83％,of which type 3b accounted for 28.70％(33/115),and Type 3a accounted for 19.13％(22/115).Multiple linear regression analysis showed that patients with occupation,high school education or above had a higher rate of antiviral therapy.Conclusions The awareness rate of knowledge about prevention and treatment and the rate of receiving anti-virus treatment in patients with hepatitis C reported in Yubei District from 2004 to 2021 were low.It is necessary to strengthen the targeted publicity and education to improve the health awareness of patients.
关键词
丙型肝炎/知晓情况/基因分型/抗病毒治疗/影响因素Key words
hepatitis C/awareness/genotyping/antiviral therapy/influencing factors引用本文复制引用
出版年
2024
NETL
NSTL
万方数据