山东省某市市售鸡蛋和鸡肉中硝基咪唑类药物残留检测分析
Monitoring results analysis of nitroimidazole drug residues in eggs and chicken from markets
张远 1葛文娜 2霍海波 3郑凤家 1姜大峰 4李华锋5
作者信息
- 1. 山东医学高等专科学校医学检验系,山东济南 250002
- 2. 曲阜市疾病预防控制中心
- 3. 山东医学高等专科学校药学系
- 4. 山东省疾病预防控制中心卫生检验检测所
- 5. 山东医学高等专科学校组织人事处
- 折叠
摘要
目的 了解山东省某市市售鸡蛋和鸡肉中硝基咪唑类药物的残留情况.方法 2021年6-8月,从山东省某市农贸市场和超市等场所采集鸡蛋样品10份、鸡肉样品30份,采用超高效液相色谱-串联质谱法(UPLC-MS/MS)测定样品中5种硝基咪唑类药物的残留量.结果 在40份样品中9份检出硝基咪唑类药物残留,检出率为22.50％(9/40).在2份鸡蛋样品中检出药物残留、检出率为20％(2/10),其中1份检出甲硝唑、含量为124 μg/kg,另外1份检出地美硝唑、含量为214 μg/kg.在30份鸡肉样品中,1份检出甲硝唑、含量为2.65 μg/kg,7份检出罗硝唑、含量为0.26～3.59 μg/kg.结论 山东省某市市售鸡蛋和鸡肉样品中存在硝基咪唑类药物残留情况.
Abstract
Objective To understand the nitroimidazole drug residues in eggs and chicken from markets.Methods The residues of 5 nitroimidazole drugs in a total of 10 egg samples and 30 chicken samples,collected from farmers'markets and supermarkets in a city of Shandong Province between June and August 2021.Samples were determined by using ultra-high performance liquid chromatography-tandem mass spectrometry(UPLC-MS/MS).Results Drug residue was detected in 9 of 40 samples,the total detection rate was 22.50％.In terms of classification,drug residues were detected in 2 egg sam-ples,the detection rate was 20％.Metronidazole(124 μg/kg)was detected in 1 sample,the content of dimecnidazole was 214 μg/kg in the other one.Metronidazole(2.65 μg/kg)was detected in 1 sample of 30 chicken samples.Ronidazole was detected in 7 samples with the content ranging from 0.26 to 3.59 μg/kg.Conclusion The presence of nitroimidazole residues was detected in eggs and chicken samples sold within a city located in Shandong province.
关键词
鸡蛋/鸡肉/硝基咪唑/药物残留/超高效液相色谱-串联质谱法Key words
Egg/Chicken/Nitroimidazole/Drug residue/UPLC-MS/MS引用本文复制引用
基金项目
山东省医药卫生科技发展计划(202112060707)
山东省医药卫生科技发展计划(202112061045)
出版年
2024
NETL
NSTL
万方数据