Analysis on survival time and influencing factors of newly reported HIV/AIDS cases aged 50 years and above in Linyi city
Objective To analyze the survival time and influencing factors of newly reported HIV/AIDS cases aged 50 years and above in Linyi city,so as to provide evidence for improve the survival time and optimize the prevention and con-trol measures.Methods A retrospective cohort study was conducted to analyze the data of HIV/AIDS cases who lived in Linyi city aged 50 years and above before December 31th,2022.Data was collected from Chinese HIV/AIDS Basic Information Management System.Life table method was applied to describe the survival status,and influencing factors of survival time were analyzed by Cox proportional regression model.Results Of the 350 HIV/AIDS cases,210 were HIV(60.00％)and 300 received antiretroviral therapy(ART).At the end point of observation,265 cases were survived and 85 cases were died.The cumulative survival rate of 1 year,3 years,5 years and 10 years after diagnosis was 78.04％,70.84％,64.04％and 57.79％.Cox multivariate analysis showed that those married(HR=0.478,95％CI:0.268-0.850,P＜0.05),with junior middle school education level(HR=0.344,95％CI:0.161-0.733,P＜0.05),received ART(HR=0.142,95％CI:0.066-0.308,P＜0.05),and the first CD4+T cell counts in 200-349(HR=0.381,95％CI:0.185-0.784,P＜0.05),350-499(HR=0.227,95％CI:0.092-0.561,P＜0.05)and ≥500 cells/μL(HR=0.359,95％CI:0.143-0.901,P＜0.05)could reduce the risk of death.Conclusion Survival of HIV/AIDS cases ≥50 years of age in Linyi city needs to be improved,with marital status,literacy,receipt of antiretroviral therapy,and first CD4 cell counts as influencing factors for survival time in this population.
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