Cost-benefit analysis on free varicella vaccination strategy for children in Qingdao city from 2013 to 2020
Objective To evaluate the cost-effectiveness of the free varicella vaccination strategy for school-age children in Qingdao city from 2013 to 2020.Methods Data on varicella vaccination in Qingdao city were collected from July 1,2013-December 31,2020 through the Shandong Province Preventive Vaccination Information System;data on the eco-nomic burden of varicella cases were obtained through a special survey of varicella-affected children.It was divided into two immunization strategy phases,the first phase was from July 1,2013 to June 30,2016,and one dose of varicella vaccine was given free of charge to children who were born after July 1,2012 and reached 1 year of age.The second phase was July 1,2016-December 31,2020,based on the first phase,the second dose of varicella vaccine was given free of charge to chil-dren who were born after July 1,2012 and had reached the age of 4 years.According to the vaccination data and cost of free varicella vaccine in Qingdao city,the vaccination cost of different immunization strategies was calculated.Data on eco-nomic burden of varicella cases were collected through special surveys.The cost-effectiveness ratio and cost-benefit ratio of different immunization strategies were calculated based on the above data.Results The cost of one dose and two doses in the two phases were 75 million yuan and 46 million yuan,respectively.The outpatient cases of varicella accounted for 96.30％,and the average economic burden was 2 895.53 yuan per person.The cost-effectiveness ratio of one dose was 0.89∶1,and the cost-benefit ratio was 23.52∶1.The cost-effectiveness ratio of two doses was 0.94∶1,and the cost-ben-efit ratio was 25.89∶1.Conclusion Two-dose varicella vaccination is superior to one-dose vaccination in both economic and social benefits.
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万方数据
