Analysis on detection of hepatitis B surface antigen in hospitalized pregnant women and timely vaccination with the first dose of hepatitis B vaccine in Jinan city from 2018 to 2022
Objective To understand the detection of hepatitis B surface antigen(HBsAg)and the implementation of blocking mother to child transmission of hepatitis B virus(HBV)among hospitalized parturients in Jinan city from 2018 to 2022,so as to provide reference for improving the prevention and control of hepatitis B in newborns.Methods Excel and SPSS software were used to analyze HBV infection in hospitalized parteriums and timely vaccination of neonatal HBV vaccine(HepB1)during 2018 to 2022 in Jinan city.The HBsAg detection rate and HBsAg positivity rate of postpartum women,the timely vaccination rate of HepB1 in newborns were calculated.The rates were compared byx2 test.Results The HBsAg detection rate of hospitalized delivery women in Jinan city from 2018 to 2022 was 97.45％to 100％,with an average of 99.21％,showing an increasing trend year by year(x2=6 296.37,P＜0.001).The HBsAg positive rate was 2.52％to 3.11％,and the average was 2.84％,which showed a decreasing trend year by year(x2=34.12,P＜0.001).The proportion of HBsAg and HBeAg double positive was 49.26％-52.37％,and the average was 50.55％,with no significant difference between different years(x2=7.37,P＞0.05).The timely vaccination rate of neonatal HepB1 from 2018 to 2022 ranged from 93.18％to 94.73％,and the average was 94.37％,the simultaneous injection rates of HepB1 and HBIG in neonates with HBsAg positive mothers ranged from 90.67 to 99.29％,and the average was 96.15％,which showed an increasing trend year by year(x2=34.13,P＜0.001).Conclusion The risk of mother-to-child transmission of hepatitis B still exists in Jinan city,maternal serological testing and neonatal HepB1 vaccination still need to be continuously monitored and improved.
PuerperaNewbornHepatitis B surface antigenHepatitis B vaccineTimely vaccination rateHepatitis B immu-noglobulin
NETL
NSTL
万方数据
