Investigation and analysis on early infection in 105 cases of latent syphilis
Objective To understand the prevalence and related factors of early latent syphilis in Guangzhou city,so as to provide scientific basis for formulating targeted prevention and control measures.Methods Using convenience sampling method,105 cases of latent syphilis confirmed and reported by Guangdong Provincial People's Hospital,the Third Affilia-ted Hospital of Southern Medical University,Guangzhou Dermatological Hospital,and Baiyun District Maternal and Child Healthcare Hospital of Guangzhou City in 2022 were selected for the survey.The general demographic characteristics,sex-ual behavior characteristics,medical history,and laboratory testing information of syphilis and HIV were collected.The characteristics and early infection status of individuals with different latent syphilis characteristics were analyzed.Results A total of 105 cases of latent syphilis were investigated,of which 74.29％(78/105)were confirmed by cutaneous vene-real departments,and 25.71％(27/105)were confirmed by non cutaneous venereal departments,80.95％(85/105)of the cases were active visitors to the outpatient services,and 19.05％(20/105)were screened for syphilis positively from the inpatient departments.The male accounted for 56.19％(59/105)and the female accounted for 43.81％(46/105).The proportion of the being married were 48.57％(51/105),while that of the singles including the unmarried,divorcees and widows were 51.43％(54/105).Rapid plasma reactin ring card test(RPR)or toluidine red unheated serum test(TRUST)had a titre＜1∶8 in 54.81％(57/104)and a titre ≥1∶8 in 45.19％(47/104).Of the 105 cases,45.71％(48/105)were early latent syphilis.The percentage of early infection were higher in cutaneous venereal departments(x2=8.083,P=0.004),active outpatient patients(x2=4.272,P=0.039),the male(x2=7.702,P=0.006),singles(x2=4.339,P=0.037),people aged 20-29 years old(x2=19.379,P＜0.001),the ones having unmarried sexual partners within the past 2 years(x2=7.430,P=0.006)and having RPR or TRUST titer≥ 1:8(x2=16.597,P＜0.001),compared to non cutaneous venereal departments,inpatient passive screeners,the female,the married,other age groups,people having none unmarried sexual partners within the past 2 years and having RPR or TRUST titer＜1∶8 respective-ly.Conclusion The proportion of early infection in latent syphilis is high and the risk of transmission is big in Guang-zhou.
NETL
NSTL
万方数据
