首页|基于CLHLS数据的睡眠状况对中国老年人抑郁、焦虑的影响

基于CLHLS数据的睡眠状况对中国老年人抑郁、焦虑的影响

Influence of sleep status on depression and anxiety onset among Chinese elderly people based on CLHLS data

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目的 探讨睡眠状况对中国老年人抑郁、焦虑的影响,为预防老年抑郁症、焦虑症提供依据.方法 收集2011-2018年北京大学中国老年健康与家庭幸福调查(CLHLS)中≥65岁老年人的健康调查数据.采用简明版流行病学研究中心抑郁量表(CES-D10)对老年人的抑郁状况进行评价,采用7项广泛性焦虑障碍(GAD-7)评分对老年人的焦虑状况进行评价.采用协方差分析比较不同睡眠时间或质量变化组老年人抑郁、焦虑评分的差异,采用多因素logistic回归分析睡眠时间或质量变化情况对老年人抑郁、焦虑的影响.结果 共纳入≥65岁的老年人1 387名,每天平均睡眠时间为7.46 h,9.88%老年人睡眠质量较差,30.21%老年人存在睡眠不足.调整性别、年龄、接受教育情况、婚姻状况、保险情况、家庭年收入、吸烟情况、饮酒情况和锻炼情况后,睡眠质量较差组、一般组CES-D10评分高于睡眠质量较好组(F=18.67),睡眠时间<7 h组CES-D10评分高于睡眠时间7~9 h组(F=100.62),睡眠质量持续不佳组、恶化组、改善组CES-D10评分均高于持续较好组(F=9.47),睡眠时间持续不足组、损失组CES-D10评分均高于持续充足组(F=28.84),以上比较差异均有统计学意义(P<0.05).调整潜在的混杂因素后,睡眠质量较差组GAD-7评分高于睡眠质量较好组(F=11.75),睡眠时间<7 h组GAD-7评分高于睡眠时间7~9 h组(F=19.46),睡眠质量持续不佳、恶化组GAD-7评分均高于持续较好组(F=5.45),睡眠时间持续不足组GAD-7评分均高于持续充足组(F=7.51),以上比较差异均有统计学意义(P<0.05).睡眠质量改善者抑郁、焦虑发生风险最低(抑郁OR=1.65,95%CI:1.17~2.33,P<0.05;焦虑 OR=1.92,95%CI:1.01~3.69,P<0.05),而恶化者(抑郁 OR=5.20,95%CI:3.90~6.93,P<0.05;焦虑 OR=2.80,95%CI:1.67~4.69,P<0.05)、持续不佳者(抑郁OR=5.13,95%CI:3.74~7.05,P<0.05;焦虑OR=4.07,95%CI:2.42~6.84,P<0.05)抑郁、焦虑的发生风险显著增加.睡眠时间增加者抑郁、焦虑的发生风险最低(抑郁 OR=1.26,95%CI:0.91~1.75,P<0.05;焦虑 OR=1.36,95%CI:0.76~2.38,P<0.05),而持续不足者(抑郁OR=2.46,95%CI:1.80~3.36,P<0.05;焦虑 OR=2.26,95%CI:1.42~3.60,P<0.05)抑郁、焦虑的发生风险显著增加.结论 睡眠时间短和睡眠质量差的老年人抑郁、焦虑的发生风险增加,而睡眠时间增长和睡眠质量改善者该风险低.
Objective To investigate the impact of sleep status on depression and anxiety in elderly Chinese individuals,so as to provide a basis for the prevention of these conditions.Methods Health survey data were collected from Peking U-niversity's"China Elderly Health and Family Happiness Survey(CLHLS)"in 2011 and 2018.The depressive status of the elderly was assessed using the Center for Epidemiologic Studies Depression Scale-10(CES-D10),and anxiety status was e-valuated using the Generalized Anxiety Disorder scale-7(GAD-7).Covariance analysis was used to compare differences in depression and anxiety scores between groups with different variations in sleep duration or quality,and a multivariate lo-gistic regression model was used to analyze the influence of changes in sleep duration or quality on depression and anxiety among the elderly.Results A total of 1 387 elderly people aged ≥65 years were included,with a mean sleep duration of 7.46 hours,9.88%of participants reported poor sleep quality,and 30.21%suffered from sleep deprivation.After adjus-ting for gender,age,education level,marital status,insurance status,annual household income,smoking status,alcohol con-sumption,and exercise habits,the CES-D10 scores were higher in the poor and average sleep quality groups compared to the good sleep quality group(F=18.67).The group with less than 7 hours of sleep had higher CES-D10 scores than those with 7-9 hours(F=100.62).Groups with persistent poor sleep,deteriorating sleep,and improved sleep all had higher CES-D10 scores than those with consistently good sleep(F=9.47).Additionally,those with consistently insuffi-cient or reduced sleep duration had higher CES-D10 scores than those with consistently sufficient sleep(F=28.84).All these differences were statistically significant(P<0.05).Adjusting for potential confounders,GAD-7 scores were higher in the poor sleep quality group than the good sleep quality group(F=11.75).Scores were also higher in those sleeping less than 7 hours compared to those sleeping 7-9 hours(F=19.46).Groups with persistent poor sleep or deteriorating sleep had higher scores than those with consistently good sleep(F=5.45).Those with consistently insufficient sleep had higher scores than those with consistently sufficient sleep(F=7.51).All these differences were statistically significant(P<0.05).Individuals who experienced improvement in sleep quality had the lowest risk of depression and anxiety(de-pression OR=1.65,95%CI:1.17-2.33,P<0.05;anxiety OR=1.92,95%CI:1.01-3.69,P<0.05),while those with deterioration(depression OR=5.20,95%CI:3.90-6.93,P<0.05;anxiety OR=2.80,95%CI:1.67-4.69,P<0.05),and those with persistent poor sleep(depression OR=5.13,95%CI:3.74-7.05,P<0.05;anxiety OR=4.07,95%CI:2.42-6.84,P<0.05)had a significantly increased risk of depression and anxiety.Similarly,those with increased sleep du-ration had the lowest risk of depression and anxiety(depression OR=1.26,95%CI:0.91-1.75,P<0.05;anxiety OR=1.36,95%CI:0.76-2.38,P<0.05)and those with consistently insufficient sleep duration(depressionOR=2.46,95%CI:1.80-3.36,P<0.05;anxiety OR=2.26,95%CI:1.42-3.60,P<0.05)had a significantly increased risk of depres-sion and anxiety.Conclusion Short sleep duration and poor sleep quality are associated with an increased risk of depres-sion and anxiety among elderly individuals,while those with increased sleep duration and improved sleep quality have a lower risk of developing these conditions.

DepressionAnxietySleep qualitySleep durationElderly

刘婷、李成、赵敏、席波

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山东大学齐鲁医学院公共卫生学院流行病学系,山东济南 250012

江苏医药职业学院公共卫生与管理学院

山东大学齐鲁医学院公共卫生学院毒理与营养学系

抑郁 焦虑 睡眠质量 睡眠时间 老年人

2024

预防医学论坛
中华预防医学会

预防医学论坛

影响因子:0.645
ISSN:1672-9153
年,卷(期):2024.30(7)