首页|2017-2023年山东省潍坊市流行性感冒病毒病原学监测结果分析

2017-2023年山东省潍坊市流行性感冒病毒病原学监测结果分析

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目的 分析2017-2023年山东省潍坊市流行性感冒(流感)病原学特点及趋势变化,为流感防控提供参考依据.方法 收集2017-2023年山东省潍坊市国家级哨点医院的流感样病例病原学监测资料及全市暴发疫情资料,采用SPSS 20.0统计软件对数据进行分析.结果 2017-2023年哨点医院共采集咽拭子样本4 241份,检出流感病毒阳性样本581份,总体阳性率13.70%,甲型H1N1流感病毒占比最高(33.56%),其次为乙型Victoria流感病毒(27.02%).除2020-2021年未检出流感病毒外,其余年度呈现不同亚型毒株共同或交替流行趋势.2017-2018年优势毒株为甲型H1N1病毒和乙型Yamagata病毒,2018-2019年优势毒株为甲型H1N1病毒和甲型H3N2病毒,2019-2020年优势株为甲型H3N2病毒,2021-2022年优势毒株为乙型Victoria病毒(100%),2022-2023年优势毒株为甲型H3N2病毒和甲型H1N1病毒.不同季节流感病毒核酸检出阳性率差异有统计学意义(x2=189.893,P<0.001),以冬春季为主.不同性别阳性检出率差异无统计学意义(x2=2.214,P>0.05),不同年龄组核酸检测阳性率差异有统计学意义(x2=205.666,P<0.001),其中15~24岁年龄组核酸检测阳性率最高(23.73%).2017-2023年共报告流感样病例暴发疫情54起,以小学(48.15%)、中学(18.52%)为主,主要由乙型Yamagata病毒引起,其次为甲型H3N2病毒和乙型Vic-toria病毒.结论 2017-2023年山东省潍坊市流感疫情呈现不同优势株共同或交替流行的态势,应重点关注学校等人群聚集场所,持续做好流感样病例监测.
Analysis on pathogenic surveillance of influenza in Weifang city,Shandong province from 2017 to 2023
Objective To analyze the etiological and incidence trend of influenza in Weifang city from 2017 to 2023,so as to provide reference for influenza prevention and control.Methods The data on the pathogenetic surveillance of influen-za-like illness(ILI)cases in national sentinel hospitals and the outbreak epidemic in Weifang city,Shandong province were collected from 2017 to 2023,and the data were analyzed by SPSS 20.0 statistical software.Results A total of 4 241 throat swab samples were collected from sentinel hospitals from 2017 to 2023,and 581 positive samples were detected,and positive rate of the influenza virus nucleic acid was 13.70%.The proportion of H1N1 influenza virus was the highest(33.56%),followed by Victoria B influenza virus(27.02%).Except for the 2020 to 2021 period when no influenza virus was detected,there was a trend of common or alternating outbreaks of different subtypes of strains in other years.The dominant strains in 2017 to 2018 were H1N1 virus and Yamagata virus,the dominant strains in 2018 to 2019 were H1N1 virus and H3N2 virus,the dominant strain in 2019-2020 was the H3N2 virus,the dominant strain in 2021 to 2022 was Vic-toria B virus(100%),the dominant strains in 2022 to 2023 were H3N2 virus and H1N1 virus.There was a statistically significant difference in the positive rate of influenza virus nucleic acid detection in different seasons(x2=189.893,P<0.001),mainly in winter and spring.There was no statistically significant difference in positive detection rates between genders(x2=2.214,P>0.05),and there was a statistically signifi-cant difference in the positive rate of influenza virus nucleic acid detection among different age groups(x2=205.666,P<0.001),the highest positive rate of nucleic acid testing was in the 15-24 age group(23.73%).A total of 54 ILI outbreaks were reported from 2017 to 2023,they were mainly occurred in primary schools(48.15%)and secondary schools(18.52%),mainly caused by the B Yamagata virus,followed by the A H3N2 virus and the B Victoria virus.Conclusion The influenza epidemic in Weifang city from 2017 to 2023 showed a trend of alternating outbreaks of different dominant strains,attention should be paid to gathering places such as schools,and continuous monitoring of ILI should be carried out.

InfluenceEtiologyTrend

姜艳艳、田蒙蒙、申亚琦、范俊杰、陈伟、单杰

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潍坊市疾病预防控制中心传染病防制科,山东 261061

潍坊市疾病预防控制中心微生物检验科

潍坊市疾病预防控制中心

流行性感冒 病原学 流行趋势

山东省潍坊市科技发展计划项目山东省潍坊市科技发展计划项目

2022ZJ10602022YX113

2024

预防医学论坛
中华预防医学会

预防医学论坛

影响因子:0.645
ISSN:1672-9153
年,卷(期):2024.30(7)