Analysis on survival status and influencing factors of reported HIV/AIDS cases in Jining city from 1996 to 2023
Objective To analyze the survival status and influencing factors of human immunodeficiency virus infection/acquired immune deficiency syndrome(HIV/AIDS)in Jining city from 1996 to 2023,so as to provide references for the development of relevant control measures.Methods The HIV/AIDS cases reported in the China AIDS Comprehensive Prevention and Control Information System from 1996 to 2023 in Jining city were analyzed retrospectively.The survival rate and survival time of cases were calculated by life table method and Kaplan-Meier method,and the factors related to survival time were analyzed by Cox proportional hazard model.Results From 1996 to 2023,a total of 1 920 HIV/AIDS cases were found in Jining city,and 316 deaths were reported,and the all-cause mortality rate was 8.31/100 person-year.The mean survival period was 20.35 years(95％CI:19.34-21.37),with 5-year and 10-year survival rates of 85％and 77％,respectively.Cox proportional hazards model analysis showed that the higher risk factors of AIDS death included the educational background of primary school education or below(HR=1.72,95％CI:1.08-2.73,P＜0.05);being found through medical institutions(HR=1.95,95％CI:1.42-2.68,P＜0.05);having a latest CD4+T lymphocyte count of 350 cells/μL(HR=3.66,95％CI:2.77-4.84,P＜0.05);no antiviral therapy was given(HR=25.63,95％CI:19.67-33.41,P＜0.05).Conclusion In the HIV/AIDS population of Jining city from 1996 to 2023,individuals with higher educational levels and those found through testing and counseling are at a lower risk of death.Additionally,the risk of death and delayed survival can be reduced by improving antiretroviral treatment coverage and timeliness,as well as by increasing CD4 cell levels.
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