首页|2021-2023年德州市病毒性腹泻病原监测分析

2021-2023年德州市病毒性腹泻病原监测分析

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目的 了解2021-2023年德州市病毒性腹泻的流行病学特征,为预防和控制病毒性腹泻提供数据基础.方法 收集2021-2023年德州市腹泻哨点监测的腹泻患者的粪便标本1 875份,采用Real-Time RT-PCR方法检测A组轮状病毒、诺如病毒GⅠ型和GⅡ型、星状病毒、札如病毒、肠道腺病毒核酸,对6种病毒检测结果进行统计学分析.结果 共检出6种病毒阳性303份,总阳性率16.16%(303/1 875),其中A组轮状病毒8.32%(156/1 875)、诺如病毒GⅠ型0.96%(18/1 875)、诺如病毒 GⅡ 型 5.28%(99/1 875)、星状病毒 1.25%(14/1 120)、札如病毒 1.25%(14/1 120)、肠道腺病毒2.32%(26/1 120).轮状病毒A组发病以6月龄~1岁阳性率最高,各年龄组阳性率差异有统计学意义(x2=71.750,P<0.001);发病时间以1-4月为高峰期,各月份阳性率差异有统计学意义(x2=63.814,P<0.001).诺如病毒GⅠ型发病以5-7月份阳性率为最高,各月份阳性率比较差异有统计学意义(x2=16.082,P=0.031).星状病毒患者发病以2~5岁阳性率最高,各年龄组阳性率差异有统计学意义(x2=17.133,P=0.027).札如病毒发病有明显的季节性趋势,以3月份阳性率最高,各月份阳性率比较差异有统计学意义(x2=58.621,P=0.035).肠道腺病毒发病有明显的季节性发病趋势,9-11月为高峰期,各月份阳性率差异有统计学意义(x2=36.86,P<0.001).结论 2021-2023年德州市病毒性腹泻发病以轮状病毒、诺如病毒和肠道腺病毒为主,5岁以下儿童是易感人群,且存在地域差异.
Analysis on viral diarrhea pathogen surveillance in Dezhou city from 2021 to 2023
Objective To understand the epidemiological characteristics of viral diarrhea in Dezhou from 2021 to 2023,so as to provide a data basis for the prevention and control of viral diarrhea.Methods A total of 1 875 stool specimens were collected at the Dezhou diarrhoea surveillance sentinels from 2021 to 2023,group A rotavirus,norovirus GⅠ and GⅡ,astrovirus,sapovirus,and enteric adenovirus nucleic acids were detected by Real-Time RT-PCR,and the results of the 6 viruses were statistically analyzed.Results A total of 303 positive cases were detected,with an overall positive rate of 16.16%(303/1 875),including group A rotavirus 8.32%(156/1 875),norovirus GⅠ0.96%(18/1 875),norovirus GⅡ5.28%(99/1 875),astrovirus 1.25%(14/1 120),sapovirus 1.25%(14/1 120),and enteric adenovirus 2.32%(26/1 120).The positive rate of group A rotavirus was highest in the age range of 6 months to 1 year,and the difference in positive rate among different age groups was statistically significant(x2=71.750,P<0.001);the peak period of onset was from January to April,and the difference in positive rate among different months was statistically significant(x2=63.814,P<0.001).The positive rate of norovirus GⅠ was highest in the age range of May to July,and the difference in positive rate among different months was statistically significant(x2=16.082,P=0.031).Astrovirus patients had the highest positive rate among the age range of 2 to 5 years,and the difference in positive rate among different age groups was statistically significant(x2=17.133,P=0.027).Sapovirus incidence had a clear seasonal trend,with the highest positive rate in March and positive rate in each month.There was a statistically significant difference in the incidence of enteric ad-enovirus(x2=58.621,P=0.035).The incidence of enteric adenovirus showed a clear seasonal trend,with the peak peri-od from September to November,and there was a statistically significant difference in the positive rate between each month(x2=36.86,P<0.001).Conclusion From 2021 to 2023,the incidence of viral diarrhoea in Dezhou city is dominated by rotavirus,norovirus and enteric adenovirus,with children under 5 years of age being the susceptible group,and there are geographic differences.

Viral diarrheaRotavirusNoriovirusAstrovirusSapovirusEnteric AdenovirusEpidemiological characteristics

张晓凤、赵玉香

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德州市临邑县疾病预防控制中心检验科,山东 251500

病毒性腹泻 轮状病毒 诺如病毒 星状病毒 札如病毒 肠道腺病毒 流行特征

2024

预防医学论坛
中华预防医学会

预防医学论坛

影响因子:0.645
ISSN:1672-9153
年,卷(期):2024.30(10)