Objective To understand the epidemiological characteristics of viral diarrhea in Dezhou from 2021 to 2023,so as to provide a data basis for the prevention and control of viral diarrhea.Methods A total of 1 875 stool specimens were collected at the Dezhou diarrhoea surveillance sentinels from 2021 to 2023,group A rotavirus,norovirus GⅠ and GⅡ,astrovirus,sapovirus,and enteric adenovirus nucleic acids were detected by Real-Time RT-PCR,and the results of the 6 viruses were statistically analyzed.Results A total of 303 positive cases were detected,with an overall positive rate of 16.16%(303/1 875),including group A rotavirus 8.32%(156/1 875),norovirus GⅠ0.96%(18/1 875),norovirus GⅡ5.28%(99/1 875),astrovirus 1.25%(14/1 120),sapovirus 1.25%(14/1 120),and enteric adenovirus 2.32%(26/1 120).The positive rate of group A rotavirus was highest in the age range of 6 months to 1 year,and the difference in positive rate among different age groups was statistically significant(x2=71.750,P<0.001);the peak period of onset was from January to April,and the difference in positive rate among different months was statistically significant(x2=63.814,P<0.001).The positive rate of norovirus GⅠ was highest in the age range of May to July,and the difference in positive rate among different months was statistically significant(x2=16.082,P=0.031).Astrovirus patients had the highest positive rate among the age range of 2 to 5 years,and the difference in positive rate among different age groups was statistically significant(x2=17.133,P=0.027).Sapovirus incidence had a clear seasonal trend,with the highest positive rate in March and positive rate in each month.There was a statistically significant difference in the incidence of enteric ad-enovirus(x2=58.621,P=0.035).The incidence of enteric adenovirus showed a clear seasonal trend,with the peak peri-od from September to November,and there was a statistically significant difference in the positive rate between each month(x2=36.86,P<0.001).Conclusion From 2021 to 2023,the incidence of viral diarrhoea in Dezhou city is dominated by rotavirus,norovirus and enteric adenovirus,with children under 5 years of age being the susceptible group,and there are geographic differences.