首页|2021-2023年德州市病毒性腹泻病原监测分析

2021-2023年德州市病毒性腹泻病原监测分析

Analysis on viral diarrhea pathogen surveillance in Dezhou city from 2021 to 2023

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目的 了解2021-2023年德州市病毒性腹泻的流行病学特征,为预防和控制病毒性腹泻提供数据基础.方法 收集2021-2023年德州市腹泻哨点监测的腹泻患者的粪便标本1 875份,采用Real-Time RT-PCR方法检测A组轮状病毒、诺如病毒GⅠ型和GⅡ型、星状病毒、札如病毒、肠道腺病毒核酸,对6种病毒检测结果进行统计学分析.结果 共检出6种病毒阳性303份,总阳性率16.16%(303/1 875),其中A组轮状病毒8.32%(156/1 875)、诺如病毒GⅠ型0.96%(18/1 875)、诺如病毒 GⅡ 型 5.28%(99/1 875)、星状病毒 1.25%(14/1 120)、札如病毒 1.25%(14/1 120)、肠道腺病毒2.32%(26/1 120).轮状病毒A组发病以6月龄~1岁阳性率最高,各年龄组阳性率差异有统计学意义(x2=71.750,P<0.001);发病时间以1-4月为高峰期,各月份阳性率差异有统计学意义(x2=63.814,P<0.001).诺如病毒GⅠ型发病以5-7月份阳性率为最高,各月份阳性率比较差异有统计学意义(x2=16.082,P=0.031).星状病毒患者发病以2~5岁阳性率最高,各年龄组阳性率差异有统计学意义(x2=17.133,P=0.027).札如病毒发病有明显的季节性趋势,以3月份阳性率最高,各月份阳性率比较差异有统计学意义(x2=58.621,P=0.035).肠道腺病毒发病有明显的季节性发病趋势,9-11月为高峰期,各月份阳性率差异有统计学意义(x2=36.86,P<0.001).结论 2021-2023年德州市病毒性腹泻发病以轮状病毒、诺如病毒和肠道腺病毒为主,5岁以下儿童是易感人群,且存在地域差异.
Objective To understand the epidemiological characteristics of viral diarrhea in Dezhou from 2021 to 2023,so as to provide a data basis for the prevention and control of viral diarrhea.Methods A total of 1 875 stool specimens were collected at the Dezhou diarrhoea surveillance sentinels from 2021 to 2023,group A rotavirus,norovirus GⅠ and GⅡ,astrovirus,sapovirus,and enteric adenovirus nucleic acids were detected by Real-Time RT-PCR,and the results of the 6 viruses were statistically analyzed.Results A total of 303 positive cases were detected,with an overall positive rate of 16.16%(303/1 875),including group A rotavirus 8.32%(156/1 875),norovirus GⅠ0.96%(18/1 875),norovirus GⅡ5.28%(99/1 875),astrovirus 1.25%(14/1 120),sapovirus 1.25%(14/1 120),and enteric adenovirus 2.32%(26/1 120).The positive rate of group A rotavirus was highest in the age range of 6 months to 1 year,and the difference in positive rate among different age groups was statistically significant(x2=71.750,P<0.001);the peak period of onset was from January to April,and the difference in positive rate among different months was statistically significant(x2=63.814,P<0.001).The positive rate of norovirus GⅠ was highest in the age range of May to July,and the difference in positive rate among different months was statistically significant(x2=16.082,P=0.031).Astrovirus patients had the highest positive rate among the age range of 2 to 5 years,and the difference in positive rate among different age groups was statistically significant(x2=17.133,P=0.027).Sapovirus incidence had a clear seasonal trend,with the highest positive rate in March and positive rate in each month.There was a statistically significant difference in the incidence of enteric ad-enovirus(x2=58.621,P=0.035).The incidence of enteric adenovirus showed a clear seasonal trend,with the peak peri-od from September to November,and there was a statistically significant difference in the positive rate between each month(x2=36.86,P<0.001).Conclusion From 2021 to 2023,the incidence of viral diarrhoea in Dezhou city is dominated by rotavirus,norovirus and enteric adenovirus,with children under 5 years of age being the susceptible group,and there are geographic differences.

Viral diarrheaRotavirusNoriovirusAstrovirusSapovirusEnteric AdenovirusEpidemiological characteristics

张晓凤、赵玉香

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德州市临邑县疾病预防控制中心检验科,山东 251500

病毒性腹泻 轮状病毒 诺如病毒 星状病毒 札如病毒 肠道腺病毒 流行特征

2024

预防医学论坛
中华预防医学会

预防医学论坛

影响因子:0.645
ISSN:1672-9153
年,卷(期):2024.30(10)