首页|妊娠期维生素A、D、E表达水平及其临床意义

妊娠期维生素A、D、E表达水平及其临床意义

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目的 探讨妊娠期维生素A、D、E的表达水平及其对不良妊娠结局的预测价值.方法 回顾性分析 2021年 11 月至 2022 年 11 月于广西医大开元琅东医院行产前检查并分娩的 90 例孕妇的临床资料.根据妊娠结局分为不良妊娠结局组(不良组,n=37)和正常妊娠结局组(正常组,n=53).收集妊娠期间相关临床资料,采用logistic回归分析影响不良妊娠结局的危险因素,采用受试者工作特征曲线(ROC)评价维生素A、D、E水平对不良妊娠结局的预测价值.结果 Logistic回归分析显示高水平的维生素A、D、E是不良妊娠的保护因素(P<0.05);维生素A、D、E预测不良妊娠结局的 AUC 分别为 0.691、0.797、0.784;三者联合预测妊娠不良结局的 AUC 为 0.906,敏感度为81.08%,特异度为 83.02%.结论 维生素A、D、E联合使用在孕妇不良妊娠结局的预测中具有较高的指导价值,可为医护人员识别不良妊娠的风险人群提供参考.
Expression levels of vitamin A,vitamin D,and vitamin E in gestational period and their clinical significance
Objective To investigate the expression levels of vitamin A,vitamin D,and vitamin E in gestational period and their predictive value for adverse pregnancy outcomes.Methods The clinical data of 90 pregnant women who received prenatal examination and delivered in Kaiyuan Langdong Hospital of Guangxi Medical University from November 2021 to No-vember 2022 were retrospectively analyzed.According to pregnancy outcomes,they were divided into adverse pregnancy out-come group(adverse group,n=37)and normal pregnancy outcome group(normal group,n=53).Relevant clinical data during pregnancy were collected,logistic regression was used to analyze risk factors that affected adverse pregnancy out-comes,and receiver operating characteristic(ROC)curve was used to evaluate the predictive value of vitamin A,vitamin D,and vitamin E levels on adverse pregnancy outcomes.Results Logistic regression analysis showed that high levels of serum vitamin A,vitamin D,and vitamin E were protective factors for adverse pregnancy outcomes in pregnant women(P<0.05).The area under the curve(AUC)of vitamin A,vitamin D,and vitamin E were 0.691,0.797,0.784,respectively.The AUC of the combined prediction of the three for adverse pregnancy outcome was 0.906,sensitivity was 81.08%,and speci-ficity was 83.02%.Conclusion The combination of vitamin A,vitamin D,and vitamin E has a high guiding value in the prediction of adverse pregnancy outcomes in pregnant women,which can provide references for medical personnel to identify the risk groups of adverse pregnancy.

gestational periodvitamin Avitamin Dvitamin Epregnancy outcome

蒙保山、廖晗献、梁丽荣、林娜

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广西医大睿谷医学检验有限公司检验科,广西南宁 530021

广西南宁市妇幼保健院检验科,广西南宁 530021

广西医大开元埌东医院检验科,广西南宁 530021

妊娠期 维生素A 维生素D 维生素E 妊娠结局

2024

右江医学
右江民族医学院附属医院

右江医学

影响因子:0.779
ISSN:1003-1383
年,卷(期):2024.52(1)
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