Value of MRI signs,immunohistochemistry and immunoinflammatory indicators in the prediction of axillary lymph node metastasis of breast cancer
Objective To investigate the value of MRI signs,immunohistochemistry and immunoinflammatory indicators in predicting axillary lymph node metastasis of breast cancer.Methods Clinical and imaging data of 57 patients with breast cancer admitted to Affiliated Hospital of Youjiang Medical University for Nationalities from January 2021 to October 2022 were retrospectively collected.They were divided into axillary lymph node metastasis group(referred to as metastasis group)and non-axillary lymph node metastasis group(referred to as non-metastasis group)according to postoperative lymph node bi-opsy results.Preoperative MRI signs,clinicopathological features and immunoinflammatory indicators of the two groups were compared,respectively.Spearman correlation was used to analyze the correlation between preoperative MRI signs,pathologi-cal immunohistochemistry and immunoinflammatory indicators and axillary lymph node metastasis of breast cancer,and re-ceiver operating characteristic(ROC)curve was drawn,and diagnostic efficacy was compared.Results A total of 57 pa-tients were collected,including 24 patients in the metastasis group and 33 patients in the non-metastasis group.There were statistically significant differences in age,lymph node short diameter,ratio of length to diameter,tumor long diameter,tumor enhancement mode,Ki-67 expression,NLR,PLR between the metastasis group and the non-metastasis group(P<0.05 or 0.01).Correlation analysis showed that,lymph node short diameter,tumor long diameter,tumor enhancement mode and Ki-67 were positively correlated with axillary lymph node metastasis(r was 0.515,0545,0.377,0.484,respectively,P<0.05),while the ratio of length to diameter was negatively correlated with axillary lymph node metastasis(r=-0.699,P<0.05).Univariate analysis showed that,the area under the curve(AUC)of single factor age,lymph node short diameter,ratio of length to diameter,tumor length diameter,tumor enhancement mode,Ki-67,NLR and PLR were 0.540,0.801,0.908,0.818,0.680,0.741,0.590 and 0.605,respectively.Conclusion MRI signs,immunohistochemistry and im-munoinflammatory indicators have important predictive value in determining whether lymph node metastasis is occurring in breast cancer patients,and can provide evidence for the selection of clinical treatment.
breast canceraxillary lymph node metastasismagnetic resonance imagingimmune inflammatory index
万方数据
维普
