Impact of Xuefu Zhuyu Decoction on blood pressure levels and vascular endothelial functions in hypertension patients
Objective To explore the effects of Xuefu Zhuyu Decoction on blood pressure levels and vascular endothelial functions in hypertensive patients.Methods A prospective study was conducted,90 hypertensive patients admitted to hos-pital from January 2022 to June 2023 were selected as study subjects,and they were divided into control group and observa-tion group by randomized numerical method,with 45 cases in each group.The control group were given conventional treat-ment,and based on which the observation group were treated with Xuefu Zhuyu Decoction.Both groups were continuously treated for 3 months.And then,clinical efficacy,blood pressure(diastolic blood pressure and systolic blood pressure),and vascular endothelial functions(nitric oxide[NO]and endothelin-1[ET-1])of the two groups were compared.Results The total effective rate of the observation group was higher than that of the control group,and difference was statistically signifi-cant(P＜0.05).After 3 months of treatment,systolic blood pressure and diastolic blood pressure decreased,and compared with the control group,decrease in the observation group was more significant(P＜0.05);NO increased and ET-1 de-creased,and compared to the control group,the changes in the observation group were more significant(P＜0.05).Conclu-sion The effect of Xuefu Zhuyu Decoction in treating hypertensive patients is remarkable,which can effectively regulate the blood pressure levels and improve the endothelial functions.
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