A cross-sectional study on the analysis of viral hepatitis infection in a hospital in Guangzhou from 2020 to 2023
Objective To investigate the infection and epidemiological characteristics of hepatitis A,B,C and E viruses in a hospital in Guangzhou,so as to provide insights for local prevention and control of viral hepatitis.Methods A cross-sectional study on the analysis was conducted on the positive rates,years,gender,and ages of outpatients,inpatients,and individuals undergoing physical examinations who underwent serum HAV-IgM antibody,HBV surface antigen,HCV antibod-y,HEV-IgG antibody,and HEV-IgM antibody detection in a hospital in Guangzhou from January 2020 to December 2023.Results Over the past four years,the positive numbers and rates of HAV-IgM antibody,HBV surface antigen,HCV anti-body,HEV-IgG antibody and HEV-IgM antibody were 40 cases(0.04％),28 120 cases(11.16％),1294 cases(0.54％),13 773 cases(15.76％)and 426 cases(0.46％),respectively.The highest positive rate was observed for HEV-IgG antibody,while the highest number of positive cases was for HBV surface antigen.The positive number and posi-tive rate of HEV-IgG antibody decreased year by year.There was statistically significant difference in the positive rates of HBV and HEV lgG between different years(P＜0.05).The positive rates of HBV,HCV and HEV-IgG in males were higher than those in females,there was statistically significant difference in the positive rates of HBV,HCV,and HEV-IgG between males and females(P＜0.05).There was statistically significant difference in the number of males and females infections with HBV surface antigen and HEV-IgG antibody in different age groups(P＜0.05).There were statistically significant differences in the positive rates of HBV surface antigen,HCV,and HEV-IgG among different age groups(P＜0.05).Con-clusion Hepatitis B remains the viral hepatitis with the largest number of infections,followed by hepatitis E,and its high positive rate should also be widely concerned.In addition,males are more infected than females in various viral hepatitis,which should be the focus of prevention and control.
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