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病理性近视脉络膜新生血管的药物治疗新进展

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病理性近视脉络膜新生血管(PM-CNV)是导致病理性近视患者视力丧失的常见并发症,其发病机制涉及机械牵拉、缺氧和炎症等诸多因素.抗血管内皮生长因子疗法是治疗PM-CNV的有效方法,雷珠单抗、阿柏西普和康柏西普等抗血管内皮生长因子药物经临床试验证实均能改善PM-CNV患者视力,但各有其特点和适用范围.本文综述了 PM-CNV 药物治疗的最新进展,以期为临床治疗该病提供参考.
Recent advances in drug treatment for choroidal neovascularization in patho-logical myopia
Pathological myopic choroidal neovascularization(PM-CNV)is a common complication leading to vision loss in patients with pathological myopia.Its pathogenesis involves various factors,including mechanical traction,hypoxia,and inflammation.Anti-vascular endothelial growth factor therapy has been proven to be effective in the treatment of PM-CNV.Clinical trials have demonstrated that anti-vascular endothelial growth factor drugs,such as ranibizumab,aflibercept,and conbercept,can improve the vision of patients with PM-CNV,each with its characteristics and applicable scope.This article reviews the latest advancements in drug treatment for PM-CNV,aiming to provide valuable reference for the clinical management of this disease.

choroidal neovascularisationanti-vascular endothelial growth factorefficacy comparisonoptical co-herence tomography

张宁晖、解孝锋、田庆梅、毕宏生

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250014 山东省济南市,山东中医药大学

250002 山东省济南市,山东中医药大学附属眼科医院,山东省中西医结合眼病防治重点实验室,山东省眼病防治研究院

脉络膜新生血管 抗血管内皮生长因子 疗效比较 光学相干断层扫描

2025

眼科新进展
新乡医学院

眼科新进展

北大核心
影响因子:0.961
ISSN:1003-5141
年,卷(期):2025.45(1)