首页|中间剂量计算模式对食管癌容积旋转调强放射治疗计划的影响

中间剂量计算模式对食管癌容积旋转调强放射治疗计划的影响

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目的 探讨中间剂量计算(IDC)模式对食管癌容积旋转调强放射治疗(VMAT)计划的影响.方法 选取 2021 年 12 月至 2022 年 8 月医院收治的 18 例食管癌患者,在Eclipse15.6 治疗计划系统上重新设计VMAT计划,分为未应用IDC模式计划和应用IDC模式计划,比较两种计划的靶区和危及器官(OARs)的剂量学差异.结果 两种计划靶区的D98、D2、Dmean、适形度指数(CI)和均匀性指数(HI)等参数比较,差异有统计学意义(P<0.05).两种计划双肺的V5、V10、V20、V30 和Dmean及脊髓 Dmax比较,差异无统计学意义(P>0.05),但应用IDC模式计划的心脏V30、V40、Dmean均低于未应用IDC模式计划,差异有统计学意义(P<0.05).结论 应用IDC模式计划较未应用IDC模式计划具有更好的靶区适形度和均匀性,同时降低了OARs剂量,因此,应用IDC模式计划可以提高食管癌VMAT计划的质量.
Effect of Intermediate Dose Calculation Module on Volumetric Modulated Arc Therapy Planning for Esophageal Cancer
Objective To investigate the effect of the use of intermediate dose calculation(IDC)module on volumetric modulated arc therapy(VMAT)planning for esophageal cancer.Methods Eighteen patients with esophageal cancer who received radiotherapy in hospital from December 2021 to August 2022 were selected retrospectively,and two group plans were designed for each patient in the Eclipse 15.6 treatment planning system:without and with IDC module,respectively.The dosimetric difference in planning target volume(PTV)and organs at risk(OARs)between two groups were compared.Results There were significant differences in D98,D2,Dmean,CI and GI of targets among plans optimized with without IDC module and with IDC module(P<0.05).Compared with without IDC module,there were no significant differences in V5、V10、V20、V30 and Dmean of lung,and Dmax of spinal cord(P>0.05).Plans with IDC module achieved less V30,V40 and Dmean of heart,the difference was statistically significant(P<0.05).Conclusions Compared with the plans without IDC module,the plans with IDC module demonstrates superior target conformity and homogeneity,and reduces the dose of OARs.Therefore,the use of IDC module in VMAT plans of esophagus cancer patients improves the plans quality.

Esophageal cancerIntermediate dose calculationVolumetric modulated arc therapyDosimetry

刘卫东、张燕慧、孙力军、叶书成、魏鹏

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济宁医学院附属医院(山东济宁 272029)

食管癌 容积旋转调强放射治疗 中间剂量计算 剂量学

济宁医学院附属医院"苗圃"科研计划项目白求恩.精医求精-晚期实体瘤科研项目济宁医学院附属医院主诊医师团队专项临床研究计划

MP-MS-2019-019STLKY0022ZZTD-MS-2023-13

2024

医疗装备
国家食品药品监督管理局北京医疗器械质量监督检验中心 北京市医疗器械检验所

医疗装备

影响因子:0.339
ISSN:1002-2376
年,卷(期):2024.37(4)
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