摘要
目的 探讨应变弹性成像(SE)联合对比增强超声(CEUS)对腮腺良恶性肿瘤的诊断价值.方法 回顾性分析 2015 年 2 月至 2023 年 5 月于医院接受诊疗的 327 例腮腺肿瘤患者的临床资料.采集患者治疗前的SE和CEUS检查数据.根据活检或术后病理组织学检查结果将患者分为良性组(263 例)和恶性组(64 例).比较两组性别、年龄、常规超声影像特征及SE、CEUS影像特征,并分析SE、CEUS单独及联合诊断腮腺良恶性肿瘤的灵敏度、特异度、阳性预测值(PPV)、阴性预测值(NPV).结果 两组病灶数量、最大直径、形态、边缘、回声特征、钙化情况比较,差异有统计学意义(P<0.05);两组SE评分、边缘增强清晰度、环状增强、增强大小、增强模式比较,差异有统计学意义(P<0.05);SE联合CEUS诊断腮腺良恶性肿瘤的灵敏度、特异度和PPV均高于SE、CEUS单独诊断,差异有统计学意义(P<0.05).结论 腮腺良恶性肿瘤的常规超声影像特征及SE、CEUS影像特征有所不同,SE、CEUS均对腮腺良恶性肿瘤具有一定诊断价值,联合诊断可提高诊断灵敏度、特异度和PPV.
Abstract
Objective To explore the diagnostic value of strain elastography(SE)combined with contrast-enhanced ultrasound(CEUS)for benign and malignant tumors of the parotid gland.Methods With the retrospective analysis of ultrasound and medical record data of 327 patients with parotid gland tumors treated in hospitals from February 2015 to May 2023,the SE and CEUS examination data of patients before treatment were collected.According to the results of biopsy or postoperative histopathological examination,patients were divided into the benign group(263 cases)and the malignant group(64 cases).The gender,age,conventional ultrasound imaging features,as well as SE and CEUS imaging features were compared between the two groups,and the sensitivity,specificity,positive predictive value(PPV),and negative predictive value(NPV)of SE and CEUS alone and in combination for the diagnosis of benign and malignant parotid tumors were analyzed.Results The number,maximum diameter,morphology,edge,echo characteristics,and calcification of lesions between the two groups were compared,and the differences were statistically significant(P<0.05);The differences in SE scores,edge enhancement clarity,circular enhancement,enhancement size,and enhancement mode between the two groups were statistically significant(P<0.05);The sensitivity,specificity,and PPV of SE combined with CEUS in diagnosing benign and malignant parotid gland tumors were higher than those of SE and CEUS alone,with statistical significance(P<0.05).Conclusions The conventional ultrasound imaging characteristics,SE and CEUS imaging characteristics of benign and malignant parotid gland tumors are different.Both SE and CEUS have certain diagnostic value for benign and malignant parotid gland tumors,and the combined diagnosis can improve the diagnostic sensitivity,specificity and PPV.
维普
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