Application of Intra Aortic Balloon Pump in Different Timing of Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction and Cardiogenic Shock
Objective To explore the application of intra aortic balloon pump(IABP)in different timing of percutaneous coronary intervention(PCI)in patients with acute myocardial infarction(AMI)and cardiogenic shock(CS).Methods With the selection of seventy AMI patients with CS who planned to undergo PCI treatment in the hospital from January 2021 to August 2023,they were randomly divided into two groups,with 35 patients in each group.Both groups received oxygen therapy,electrocardiogram monitoring,basic medication,and emergency PCI treatment.IABP was implanted before and after PCI in the experimental group and control group,respectively.The levels of hemodynamic indicators[mean arterial pressure(MAP),heart rate(HR)and urine volume]before and 24 h after surgery,myocardial injury markers[creatine kinase MB(CK-MB)and cardiac troponin I(cTnI)]before and 7 days after surgery,cardiac function indicators[left ventricular ejection fraction(LVEF),pulmonary capillary wedge pressure(PCWP),and cardiac index(CI)]before and 3 months after surgery in both groups were compared,as well as mortality within 30 days after surgery.Results 24 h after surgery,MAP and urine volume of both groups were higher than before surgery,HR was lower than before surgery,and MAP and urine volume of experimental group were higher than control group.In addition,HR was lower than control group,the differences were statistically significant(P<0.05);7 days after surgery,serum CK-MB and cTnI levels in 2 groups were lower than before surgery,and the experimental group was lower than the control group,the differences were statistically significant(P<0.05);Three months after surgery,LVEF and CI levels in both groups were higher than before surgery,PCWP levels were lower than before surgery,LVEF and CI levels in experimental groups were higher than control group,and PCWP levels were lower than control group,with statistical significance(P<0.05).Within 30 days after operation,there was no significant difference in mortality between the two groups(P>0.05).Conclusion The application of IABP before PCI in AMI patients with CS can improve hemodynamic indexes,reduce myocardial damage and improve cardiac function more than that after PCI.
万方数据
维普
