The Combination of Qingyi Tang and Colonic Pathway Therapy Instrument is Effective for the Effects of Pancreatic Function and Inflammatory Factors in Patients with Severe Acute Pancreatitis
Objective To explore the effects of Qingyi Tang combined with colon approach therapy on pancreatic function and inflammatory factors in patients with severe acute pancreatitis.Methods A total of 116 patients with severe acute pancreatitis who were hospitalized in hospitals from January 2021 to December 2022 were selected and randomly divided into an observation group and a control group using a random number table method,with 58 cases in each group.The control group was treated with a colon pathway treatment instrument combined with rhubarb concentrated decoction,while the observation group was treated with a colon pathway treatment instrument combined with Qingyi decoction.The clinical effects,traditional Chinese medicine syndrome scores,lactate levels,pancreatic function,inflammatory factors,and adverse reactions of the two groups were compared.The total effective rate of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05);The TCM syndrome score of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05);The lactate level in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05);The insulin(INS)in the observation group was higher than that in the control group,with a statistically significant difference(P<0.05).Glucose(GLU),blood amylase(AMY),and trypsinogen-2(TPS2)were lower than those in the control group,with a statistically significant difference(P<0.05);After treatment,the levels of interleukin-6(IL-6)and tumor necrosis factor(TNF-α)and interleukin-8 in the observation group were lower than those in the control group,and the difference was statistically significant(P<0.05);There was no statistically significant difference in adverse reactions between the two groups(P>0.05).Conclusion The combination of Qingyi Tang and colon pathway therapy device can improve pancreatic function in patients with severe acute pancreatitis,promote the recovery of intestinal mucosal barrier function,alleviate inflammatory reactions in the body,and improve clinical symptoms.
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