The Application of Different Registration Methods in Image Guided Radiotherapy for Esophageal Cancer
Objective To explore the application effects of different registration methods in image guided radiotherapy(IGRT)for esophageal cancer.Methods With the selection of 24 esophageal cancer patients who underwent IGRT in the hospital from August 2022 to August 2023,all patients underwent cone beam computed tomography(CBCT)scans using X-ray volume imaging(XVI)system before treatment.In addition,three methods(automatic grayscale registration,automatic bone registration,and manual registration)were used for image registration,respectively.The registration results and time consumption of different registration methods were compared;With the manual registration results as the standard for positioning error,the differences between automatic grayscale registration and automatic bone registration after excluding positioning errors were compared.Results The registration results of the three methods in the left and right(x)directions are-1.05(-3.75,0.40),-1.00(-3.08,0.23),-0.90(-2.88,0.33)mm,and the registration results in the head and foot(y)directions are(-0.78±3.50),(0.51±3.95),and(0.64±3.97)mm,respectively;The registration results in the front and back(z)directions were-2.25(-6.15,0.40),-3.40(-5.34,0.60),and-3.20(-5.33,0.70)mm,respectively,with no statistically significant differences(P>0.05);The registration times of the three methods were(2.56±0.42),(2.17±0.58),and(52.15±14.51)s,respectively,with statistically significant differences(P<0.05).After excluding positioning errors,there was a statistically significant difference in the deviation values between automatic grayscale registration and automatic bone registration in the y and z directions(P<0.05).Conclusions Automatic grayscale registration,automatic bone registration,and manual registration can all be used for image registration of esophageal cancer IGRT.After weighing accuracy and time cost,it is recommended to use automatic bone registration.
X-ray volume imagingImage-guided radiotherapyEsophageal cancerAutomatic grayscale registrationAutomatic bone registrationManual registration