摘要
化学发光免疫分析是利用化学发光测定原理和免疫反应进行人体样本定量检测的技术,具有灵敏度高、线性范围宽等优势,被广泛应用于临床.为了解决前代全自动化学发光免疫分析仪的反应盘系统测试速度低、稳定性差等不足,该研究优化设计了一款大容量反应盘系统,并对该系统中的关键组件进行了优化分析说明.经试验验证,优化后的反应盘系统在反应盘体积不变的情况下增大了容量,同时提高了磁分离、暗室和恒温孵育稳定性等反应盘的综合性能.
Abstract
With the advantages such as high sensitivity and wide linear range,chemiluminescence immunoassay,as a technique that utilizes the principle of chemiluminescence and immune reactions for quantitative detection of human samples,is widely used in clinical practice.In onter to address the shortcomings of the reaction disk system of the previons generation luminescent immunoassay analyzer,snch as lowteting specal and poor stability,a large capacity reaction disk system was optimized and designed in this study,and key components of the system were optimized,analyzed,and explained.Through experimental verification,the optimized reaction module system increased the capacity under the condition of the same volume of the reaction plate,and improved the comprehensive performance of the reaction module such as magnetic separation,dark chamber and constant temperature incubation stability.
基金项目
上海市科学技术委员会科研计划项目(21S31906700)
NETL
NSTL
万方数据